PMID: 6403386Apr 18, 1983Paper

Caldesmon, a calmodulin-binding, F actin-interacting protein, is present in aorta, uterus and platelets

FEBS Letters
R KakiuchiS Kakiuchi

Abstract

Caldesmon, a protein originally found in chicken gizzard, was concluded also to be present in bovine aorta, uterus, and human platelets by demonstration of a protein with the following properties: (a) Ca2+-dependent calmodulin-binding; (b) binding to F actin in such way that the binding was broken on Ca2+-dependent binding of calmodulin; (c) cross-reactivity in immune blotting procedures with affinity-purified antibody against gizzard caldesmon; (d) similar subunit Mr-values on SDS-gel to those of gizzard caldesmon. Like gizzard caldesmon, platelet caldesmon was composed of two polypeptide bands of Mr 150 000 and 147 000, but caldesmon in aorta and uterus gave a single band of Mr 150 000. A polypeptide of Mr 165 000 that was immunologically distinct from caldesmon but, like caldesmon, bound to calmodulin and F actin in a flip-flop fashion, was also demonstrated in aorta and uterus.

References

Jan 1, 1978·Annual Review of Medicine·T P Stossel
Sep 1, 1979·Proceedings of the National Academy of Sciences of the United States of America·H TowbinJ Gordon
Jan 1, 1976·Journal of Biochemistry·S Ebashi
Apr 1, 1989·Proceedings of the National Academy of Sciences of the United States of America·A InoueT Masaki
Jan 1, 1981·Annual Review of Physiology·D J Hartshorne, R F Siemankowski
Feb 1, 1980·European Journal of Biochemistry·H Strzelecka-GołaszewskaW Drabikowski
Sep 1, 1981·Proceedings of the National Academy of Sciences of the United States of America·K SobueS Kakiuchi
Jan 1, 1980·Annals of the New York Academy of Sciences·R K CarlinP Siekevitz

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Citations

Jan 1, 1984·Cell and Tissue Research·H FujitaS Kakiuchi
May 1, 1984·Proceedings of the National Academy of Sciences of the United States of America·M K OwadaS Kakiuchi
Aug 1, 1985·Proceedings of the National Academy of Sciences of the United States of America·K SobueS Kakiuchi
Apr 1, 1987·Proceedings of the National Academy of Sciences of the United States of America·K SobueY Fujio
Sep 15, 1986·European Journal of Biochemistry·G PrulièreE der Terrossian
May 15, 1989·European Journal of Biochemistry·B GałazkiewiczR Dabrowska
Oct 31, 2009·The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society·Christoph N Köhler
Jan 1, 1989·American Journal of Obstetrics and Gynecology·S Marston
Mar 15, 1985·Biochemical and Biophysical Research Communications·P K Ngai, M P Walsh
May 6, 1985·FEBS Letters·B GałazkiewiczR Dabrowska
Nov 1, 2005·Developmental Dynamics : an Official Publication of the American Association of Anatomists·Leigh A ComptonJoey V Barnett
Dec 1, 1986·Journal of Muscle Research and Cell Motility·W Lehman
Dec 1, 1985·Journal of Muscle Research and Cell Motility·S B Marston, C W Smith
Jun 5, 1986·Biochimica Et Biophysica Acta·C DutoitR Aquaron

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