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Calibrating the Human Mutation Rate via Ancestral Recombination Density in Diploid Genomes

bioRxiv

Feb 20, 2015

Mark LipsonDavid E. Reich

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Abstract

The human mutation rate is an essential parameter for studying the evolution of our species, interpreting present-day genetic variation, and understanding the incidence of genetic disease. Nevertheless, our current estimates of the rate are uncertain. Most notably, recent approaches bas...read more

Mentioned in this Paper

Divergence
Species
Legal Fine
Study
Single Nucleotide Polymorphism
Mutation Abnormality
Genetic Pedigree
Population Group
Genome
Pongidae
26
1
40
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  • Calibrating the Human Mutation Rate via Ancestral Recombination Density in Diploid Genomes

    bioRxiv

    Feb 20, 2015

    Mark LipsonDavid E. Reich

    PMID: 990015560

    DOI: 10.1101/015560

    Abstract

    The human mutation rate is an essential parameter for studying the evolution of our species, interpreting present-day genetic variation, and understanding the incidence of genetic disease. Nevertheless, our current estimates of the rate are uncertain. Most notably, recent approaches bas...read more

    Mentioned in this Paper

    Divergence
    Species
    Legal Fine
    Study
    Single Nucleotide Polymorphism
    26
    1
    40

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