Callithrix penicillata as a nonhuman primate model for strongyloidiasis

Primates; Journal of Primatology
A L de MeloWanderlany Amâncio Martins


In order to better understand experimental strongyloidiasis in small New World primates, and to evaluate aspects of reinfection and immunosuppression induced by glucocorticoids, nine specimens of Callithrix penicillata (Primates: Cebidae) were administered (by subcutaneous injection, sc) 3000 infective larvae of a strain of Strongyloides venezuelensis (Rhabditida: Strongyloididae) that had been maintained in successive passages through AKR/J mice since 1987. The mean prepatent period was 5.6 ± 0.7 days post-infection (DPI). The mean patent period of infection among the untreated animals (marmosets 1-7) was 123.4 ± 61.4 DPI. Two animals (marmosets 8 and 9) received dexamethasone (2.5 mg/kg, sc) for five consecutive days starting on the 20th day after infection, but this treatment did not alter the course of the infection, and the patent period for these animals was 100.5 ± 58.7 DPI (59 and 142, respectively). Stool examination showed that the highest quantities of parasite eggs were expelled between the 8th and 19th days after inoculation of the larvae. Thereafter, there was a gradual reduction in the number of parasite eggs in feces of all marmosets. During the chronic phase of the infection, before completely negative parasito...Continue Reading


May 1, 1978·The American Journal of Tropical Medicine and Hygiene·C E Olson, E L Schiller
May 1, 1992·Veterinary Surgery : VS·T MiyabayashiP A Manley
Nov 1, 1991·Reviews of Infectious Diseases·D O Freedman
Feb 1, 1990·International Journal for Parasitology·Y Sato, H Toma
Jun 1, 1989·Journal of Helminthology·D A DenhamC M Hetherington
Mar 1, 1987·Zentralblatt Für Bakteriologie, Mikrobiologie, Und Hygiene. Series A, Medical Microbiology, Infectious Diseases, Virology, Parasitology·P B Nielsen, M Mojon
Mar 1, 1966·The American Journal of Tropical Medicine and Hygiene·K S Warren, J Simões
Aug 1, 1993·International Journal for Parasitology·A I KhanY Nawa
Jan 2, 2003·The Korean Journal of Parasitology·Byeong-Kirl BaekI Kakoma
Jun 1, 2006·Clinical and Molecular Allergy : CMA·Raja S VadlamudiGuha Krishnaswamy
Mar 31, 2009·Transactions of the Royal Society of Tropical Medicine and Hygiene·Annette OlsenPascal Magnussen
Sep 3, 2009·American Journal of Primatology·Michael L Power, E Wilson Myers

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