Callus stimulation in distraction osteogenesis

Plastic and Reconstructive Surgery
Mehrdad M MofidCraig A Vander Kolk

Abstract

Distraction osteogenesis has been described as in vivo tissue engineering. The ability to stimulate this process for the repair of bony defects or lengthening of congenitally shortened facial structures is likely to significantly impact the field of craniofacial surgery. The purpose of this study was to determine whether mechanical stimulation of the distracted rabbit mandible would accelerate the maturation of the bony callus when applied during the early consolidation period. Twenty adult New Zealand White rabbits underwent unilateral mandibular osteotomy. A uni-directional internal distractor device (Synthes, Paoli, Pa.) was positioned along a plane perpendicular to the line of osteotomy. After a 7-day latency period, distraction was commenced at a rate of 1.0 mm/day for 12 days in all animals. In a control group of 10 rabbits, a consolidation period of 8 weeks was observed before they were killed. In the experimental group of 10 rabbits, daily alternate compression and distraction of 1 mm (sequential compression and distraction) was performed for 3 weeks followed by a 5-week period of rigid fixation. Each animal received a dose of a fluorescent label at three different time points during the study: at the end of the distrac...Continue Reading

References

Jan 1, 1992·Plastic and Reconstructive Surgery·J G McCarthyB H Grayson
Jul 1, 1991·The Journal of Bone and Joint Surgery. British Volume·J KenwrightJ H Newman
Aug 1, 1990·Calcified Tissue International·R B MartinG A Dannucci
Jan 1, 1985·Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society·K E Lee, R R Pelker
Aug 1, 1984·The Journal of Bone and Joint Surgery. British Volume·G De BastianiL Renzi Brivio
Nov 1, 1994·The Journal of Craniofacial Surgery·J GuerrissiD Fiz
Nov 1, 1994·Journal of Oral and Maxillofacial Surgery : Official Journal of the American Association of Oral and Maxillofacial Surgeons·L CalifanoG Tajana
Jul 1, 1994·Plastic and Reconstructive Surgery·Y KomuroY Yonemara
Jul 1, 1996·Journal of Pediatric Orthopedics·B KassisJ C Pouliquen
Sep 24, 1998·Journal of Pediatric Orthopedics·B KassisJ C Pouliquen
Oct 20, 1998·Journal of Cranio-maxillo-facial Surgery : Official Publication of the European Association for Cranio-Maxillo-Facial Surgery·K TavakoliM D Poole
Mar 17, 1999·Plastic and Reconstructive Surgery·U MeyerU Joos
Mar 4, 2000·The Journal of Bone and Joint Surgery. British Volume·L ClaesL Kinzl
May 9, 2000·Journal of Oral and Maxillofacial Surgery : Official Journal of the American Association of Oral and Maxillofacial Surgeons·M J TroulisL B Kaban
Oct 29, 2000·Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society·R H MeffertE Y Chao
Oct 18, 2001·Plastic and Reconstructive Surgery·M M MofidC A Vander Kolk

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Citations

May 29, 2013·International Orthopaedics·Alexander V GubinTatiana A Malkova
Jul 20, 2007·Cell and Tissue Research·Lisa R AmirAntonius L J J Bronckers
Apr 23, 2013·Journal of Plastic, Reconstructive & Aesthetic Surgery : JPRAS·Paul HongMichael Bezuhly
Sep 30, 2003·Current Opinion in Otolaryngology & Head and Neck Surgery·Raam S Lakhani, Sherard A Tatum
Jul 12, 2011·The Cleft Palate-craniofacial Journal : Official Publication of the American Cleft Palate-Craniofacial Association·Peter J Taub, Joshua A Lampert
Mar 7, 2014·Clinical Orthopaedics and Related Research·Dong Hoon LeeYoung Rak Choi
Sep 18, 2013·Journal of Oral and Maxillofacial Surgery : Official Journal of the American Association of Oral and Maxillofacial Surgeons·Amera AlkaisiNoor Hayati Abd Razak
Aug 22, 2012·Journal of Oral and Maxillofacial Surgery : Official Journal of the American Association of Oral and Maxillofacial Surgeons·Sevin OzgülAydin Sav
May 24, 2011·Journal of Oral and Maxillofacial Surgery : Official Journal of the American Association of Oral and Maxillofacial Surgeons·Lucy K NagashimaMohammed E Elsalanty
Jan 25, 2011·Journal of Oral and Maxillofacial Surgery : Official Journal of the American Association of Oral and Maxillofacial Surgeons·Ufuk TatliSait Polat
Jun 15, 2010·Journal of Oral and Maxillofacial Surgery : Official Journal of the American Association of Oral and Maxillofacial Surgeons·Uk-Kyu KimGyoo-Cheon Kim
Feb 5, 2004·International Journal of Oral and Maxillofacial Surgery·H TerheydenD C Rueger
Sep 8, 2007·International Journal of Oral and Maxillofacial Surgery·N SaulacicA G Garcia
Jul 28, 2007·Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics·Ozgür ErdoğanMartin A Freilich
Jan 24, 2007·Journal of Oral and Maxillofacial Surgery : Official Journal of the American Association of Oral and Maxillofacial Surgeons·Nikola SaulacićAbel García García
Mar 15, 2006·Dental Clinics of North America·Derrick C WanMichael T Longaker
Jan 13, 2009·Veterinary Surgery : VS·Denis VerwilghenSigrid Grulke
May 4, 2004·Journal of Oral and Maxillofacial Surgery : Official Journal of the American Association of Oral and Maxillofacial Surgeons·Abel García GarcíaJose Manuel Gandara Rey
Sep 20, 2006·Journal of Oral and Maxillofacial Surgery : Official Journal of the American Association of Oral and Maxillofacial Surgeons·Uk-Kyu KimChing-Chang Ko
Jan 18, 2006·Journal of Oral and Maxillofacial Surgery : Official Journal of the American Association of Oral and Maxillofacial Surgeons·Ozgür ErdoganFiliz Cevlik
Dec 20, 2005·Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics·Jorge CanoAntonio Bascones
Jan 8, 2005·Clinics in Plastic Surgery·Randall P NacamuliMichael T Longaker
Apr 15, 2005·Seminars in Pediatric Neurology·Jack C YuGuigen Zhang
Sep 23, 2003·The Journal of Craniofacial Surgery·Mehrdad M MofidPaul N Manson
Jul 23, 2011·The Journal of Craniofacial Surgery·Jong-Tae ParkHee-Jin Kim
Jan 19, 2007·Plastic and Reconstructive Surgery·Zhen ShaoLing Liu
Apr 11, 2016·ACS Biomaterials Science & Engineering·Sarita R ShahAntonios G Mikos

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