Caloric restriction diminishes the pressor response to static exercise

Extreme Physiology & Medicine
John P FlorianJames A Pawelczyk

Abstract

Astronauts in space consume fewer calories and return to earth predisposed to orthostatic intolerance. The role that caloric deficit plays in the modulation of autonomic control of the cardiovascular system is unknown. Therefore, the purpose of this study was to determine the effects of 6° head-down bedrest (an analog of spaceflight) with a hypocaloric diet (25 % caloric restriction) (CR) on autonomic neural control during static handgrip (HG) and cold pressor (CP) tests. Nine healthy young men participated in a randomized crossover bedrest (BR) study, consisting of four, two-week interventions (hypocaloric ambulatory, hypocaloric bedrest, normocaloric ambulatory, and normocaloric bedrest), each separated by 5 months. Heart rate (HR), arterial pressure, and muscle sympathetic nerve activity (MSNA) were recorded before, during, and after HG (40 % of maximum voluntary contraction to fatigue), post-exercise muscle ischemia (forearm occlusion), and CP. Bedrest and nutritional combinations were compared using two-way ANOVA with repeated measures. HR, MSNA, and the change in systolic blood pressure during HG were attenuated with caloric restriction, but post-intervention responses for all groups were similar during post-exercise musc...Continue Reading

References

Mar 1, 1979·Journal of Applied Physiology: Respiratory, Environmental and Exercise Physiology·J V NixonC G Blomqvist
Jun 24, 1977·Science·J B Young, L Landsberg
Jan 1, 1992·The Japanese Journal of Physiology·K YamamotoT Mano
Aug 1, 1990·Journal of Applied Physiology·L B Rowell, D S O'Leary
Jul 1, 1972·The Journal of Physiology·D I McCloskey, J H Mitchell
Dec 1, 1994·Journal of Applied Physiology·J McClainL I Sinoway
Nov 1, 1993·The Journal of Clinical Investigation·J McClainL Sinoway
Jul 1, 1996·Journal of Applied Physiology·B E ShykoffR A Morin
Aug 1, 1996·Journal of Applied Physiology·B D LevineC G Blomqvist
Jun 5, 1998·Clinical Autonomic Research : Official Journal of the Clinical Autonomic Research Society·V A ConvertinoJ Vernikos
Apr 12, 2001·American Journal of Physiology. Heart and Circulatory Physiology·J A PawelczykB D Levine
Aug 22, 2001·European Journal of Applied Physiology·J SpaakD Linnarsson
Aug 23, 2001·Autonomic Neuroscience : Basic & Clinical·M PaganiA Malliani
Jan 5, 2002·The Journal of Physiology·Benjamin D LevineC Gunnar Blomqvist
Apr 18, 2002·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·T D WilliamsJ M Overton
May 3, 2002·Clinical and Experimental Pharmacology & Physiology·R A L DampneyT Tagawa
Feb 26, 2003·The American Journal of Clinical Nutrition·Pao-Hwa LinUNKNOWN DASH Collaborative Research Group
Jan 1, 2004·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·Atsunori KamiyaTadaaki Mano
Sep 15, 2004·Experimental Physiology·James P Fisher, Michael J White
Nov 6, 2004·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·George N Wade, Juli E Jones
Apr 28, 2005·Nature Neuroscience·Tony K T LamLuciano Rossetti
Aug 16, 2005·Journal of Applied Physiology·Christiane HesseWalter E Haefeli
Nov 25, 2005·Journal of Applied Physiology·Todd TrappeDavid Costill
Apr 4, 2006·FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology·Donald E MagerMark P Mattson
Aug 9, 2007·The American Journal of Clinical Nutrition·Gianni BioloGianfranco Guarnieri
Aug 21, 2013·Journal of Applied Physiology·John P FlorianBarbara E Shykoff

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