PMID: 9001714Nov 25, 1996Paper

Calretinin mRNA and immunoreactivity in the medullary reticular formation of the rat: colocalization with glutamate receptors

Brain Research
L WinskyD M Jacobowitz

Abstract

Calretinin-positive cells were identified in the medullary reticular formation of the rat by both immunohistochemistry and in situ hybridization histochemistry. In addition, double immunocytochemical labeling was used to examine the degree of colocalization of calretinin with GluR2/R3, GluR4 and GluR5-7 glutamate receptor subtypes. Results indicated regional variation in calretinin expression across reticular formation regions with the exception of the largest cells which were mostly calretinin-positive. Calretinin mRNA was particularly abundant in the parvocellular reticular nucleus. Most calretinin-immunoreactive cells also expressed at least one of the glutamate receptor subtypes examined with the exception of the smallest calretinin-positive cells of the parvocellular reticular formation which were generally not immunoreactive for any of the glutamate receptors examined. Calretinin immunoreactivity was colocalized with immunoreactivity for all three glutamate receptor subtypes examined in most of the large cells of the reticular formation. Immunoreactivity for the GluR4 antibody was least abundant in the reticular formation and GluR4 immunoreactive cells were least likely to co-express calretinin. These results suggest that...Continue Reading

Citations

Oct 12, 2000·Journal of Neurophysiology·T HajnikJ M Siegel
Apr 21, 2007·The Journal of Comparative Neurology·Su Ying ChangBernardo Rudy
Dec 19, 2009·The Journal of Comparative Neurology·Theresa PuthusseryW Rowland Taylor
May 17, 2014·Neurogastroenterology and Motility : the Official Journal of the European Gastrointestinal Motility Society·T HosoyaS Horie
May 10, 2002·Hippocampus·Carrie T Drake, Teresa A Milner
May 12, 2007·The Journal of Comparative Neurology·Hong-Ping Xu, Ning Tian
Mar 18, 2010·The Journal of Comparative Neurology·Norimitsu Suzuki, John M Bekkers
May 28, 2011·The Journal of Comparative Neurology·Peter C BrunjesJ P Arrivillaga
Dec 24, 2004·Neurotoxicity Research·David M Jacobowitz
Apr 22, 2008·The Journal of Comparative Neurology·Hong-Ping Xu, Ning Tian
Feb 27, 2010·The Journal of Comparative Neurology·Cezar GavriloviciMichael O Poulter
Aug 2, 2002·Journal of Neurobiology·Sang-Soep NahmLouise C Abbott
Oct 19, 2011·The Journal of Comparative Neurology·Theresa PuthusserySilke Haverkamp
Apr 16, 2010·The Journal of Comparative Neurology·Gabriel LepousezCécile Viollet
Dec 5, 1997·Brain Research. Molecular Brain Research·K I StraussD M Jacobowitz

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