Cameroonemide A: a new ceramide from Helichrysum cameroonense

Journal of Asian Natural Products Research
Kakam Zanetsie AntoineKarsten Krohn

Abstract

From the extracts of all parts of the plant Helichrysum cameroonense, five compounds were isolated and identified. One of them, a ceramide, named cameroonemide A (1), is reported for the first time as a new natural product. Its structure was determined by comprehensive analyses of their 1D and 2D NMR and HR-EI-MS spectral data. The remaining four known compounds were identified by comparing their spectroscopic data with those reported in the literature as kaurenoic acid (2), 3-acetyloxykaurenoic acid (3), beta-sitosterol (4), and beta-sitosterol glucopyranoside (5). Preliminary studies showed that 3-acetyloxykaurenoic acid (3) inhibited the alga Chlorella fusca, while kaurenoic acid (2) showed strong antibacterial activity against Bacillus megaterium.

References

Sep 29, 2001·Phytochemistry·L D KongR X Tan
May 31, 2002·Chemical & Pharmaceutical Bulletin·Yasunori YaoitaMasao Kikuchi
Aug 8, 2002·Fitoterapia·J R Zgoda-PolsJ R Porter
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Jan 8, 2004·Chemical & Pharmaceutical Bulletin·Pittaya TuntiwachwuttikulWalter Charles Taylor

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Citations

Jan 22, 2011·Journal of Asian Natural Products Research·Tsague Dongmo ChristelleKarsten Krohn
May 31, 2011·Journal of Asian Natural Products Research·Hidayat HussainKarsten Krohn
May 31, 2011·Journal of Asian Natural Products Research·Hidayat HussainSaeed Anwar
Mar 2, 2012·Journal of Asian Natural Products Research·Hidayat HussainLiaqat Ali
Sep 12, 2012·Natural Product Research·Hidayat HussainWen Zhang
Mar 5, 2013·International Journal of Molecular Sciences·Rouba Hage-SleimanGhassan Dbaibo
Mar 7, 2018·Chemistry & Biodiversity·Silvia GiovanelliLuisa Pistelli
Oct 4, 2017·Journal of Asian Natural Products Research·Meng-Yue WangXiao-Bo Li
Jan 24, 2012·Journal of Asian Natural Products Research·Javid HussainAhmed Al-Harrasi

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