PMID: 9178262Apr 1, 1997Paper

Camguk, Lin-2, and CASK: novel membrane-associated guanylate kinase homologs that also contain CaM kinase domains

Mechanisms of Development
S D DimitratosP J Bryant

Abstract

MAGUKs (membrane-associated guanylate kinase homologs) are proteins involved in cell junction organization, tumor suppression, and signalling. Their structure includes one or three copies of a DHR or PDZ domain (discs-large homologous region or PSD-95/SAP90, discs-large ZO-1 homologous domain), an SH3 domain, and a guanylate kinase domain. MAGUKs were classified into two subfamilies: Dlg-like with three DHR/PDZ domains and p55-like with a single DHR/PDZ domain. There is now a new subfamily whose members have a novel domain structure: a calcium/calmodulin-dependent protein kinase domain in the N-terminus as well as the DHR/PDZ, SH3 and GUK domains in the C-terminus. These new MAGUKs may regulate transmembrane molecules that bind calcium, calmodulin, or nucleotides, camguk (cmg) is a Drosophila member of this novel MAGUK subfamily; we report its sequence and domain structure.

Citations

Oct 12, 1999·BioEssays : News and Reviews in Molecular, Cellular and Developmental Biology·S D DimitratosP J Bryant
Jun 21, 2001·Biochemical and Biophysical Research Communications·C LopesM Rachidi
Sep 8, 1998·Current Opinion in Genetics & Development·S TsunodaC S Zuker
Jul 28, 2005·Critical Reviews in Plant Sciences·P V Sathyanarayanan, B W Poovaiah
Jul 31, 1998·Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences·C HagiosM J Bissell
Dec 20, 2008·Cellular & Molecular Biology Letters·Haifeng WengLawrence M Schwartz
Feb 9, 2007·Proceedings of the National Academy of Sciences of the United States of America·Deniz AtasoyThomas C Südhof
Dec 2, 2004·Brain Research. Brain Research Reviews·Jimena Sierralta, Carolina Mendoza
Jul 19, 2013·Biochemical Society Transactions·Leslie LaConte, Konark Mukherjee
Sep 29, 2009·The International Journal of Biochemistry & Cell Biology·Qizhi Sun, Gregory M Kelly
Aug 9, 2011·Molecular and Cellular Neurosciences·Kaiyun Chen, David E Featherstone
Oct 27, 1998·Genomics·H G Laverty, J B Wilson
Apr 24, 2002·Oncogene·Yasunori YamamotoYoshimi Takai
Jul 6, 2004·Molecular Reproduction and Development·Heather R BurkinDavid J Miller
May 10, 2017·Omics : a Journal of Integrative Biology·Babylakshmi MuthusamyHarsha Gowda
Jul 4, 2008·Neuroreport·María Verónica SaavedraUrsula Wyneken
Aug 22, 2007·Trends in Cell Biology·J D Wasserman, M Freeman

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