CaMsrB2, pepper methionine sulfoxide reductase B2, is a novel defense regulator against oxidative stress and pathogen attack.

Plant Physiology
Sang-Keun OhDoil Choi

Abstract

Reactive oxygen species (ROS) are inevitably generated in aerobic organisms as by-products of normal metabolism or as the result of defense and development. ROS readily oxidize methionine (Met) residues in proteins/peptides to form Met-R-sulfoxide or Met-S-sulfoxide, causing inactivation or malfunction of the proteins. A pepper (Capsicum annuum) methionine sulfoxide reductase B2 gene (CaMsrB2) was isolated, and its roles in plant defense were studied. CaMsrB2 was down-regulated upon inoculation with either incompatible or compatible pathogens. The down-regulation, however, was restored to the original expression levels only in a compatible interaction. Gain-of-function studies using tomato (Solanum lycopersicum) plants transformed with CaMsrB2 resulted in enhanced resistance to Phytophthora capsici and Phytophthora infestans. Inversely, loss-of-function studies of CaMsrB2 using virus-induced gene silencing in pepper plants (cv Early Calwonder-30R) resulted in accelerated cell death from an incompatible bacterial pathogen, Xanthomonas axonopodis pv vesicatoria (Xav) race 1, and enhanced susceptibility to a compatible bacterial pathogen, virulent X. axonopodis pv vesicatoria race 3. Measurement of ROS levels in CaMsrB2-silenced p...Continue Reading

References

Jul 25, 1990·Nucleic Acids Research·C K ShewmakerW R Hiatt
Jul 27, 1966·Biochimica Et Biophysica Acta·R C Doney, J F Thompson
Jan 1, 1995·Biochemical Society Symposium·K J Davies
Mar 25, 1998·Biophysical Journal·J GaoT C Squier
Nov 25, 1998·Proceedings of the National Academy of Sciences of the United States of America·J MoskovitzE R Stadtman
Jun 9, 1999·Mechanisms of Ageing and Development·R L LevineE R Stadtman
Nov 26, 1999·Proceedings of the National Academy of Sciences of the United States of America·R MittlerB E Ellis
Feb 17, 2001·The Journal of Physiology·T Hoshi, S Heinemann
Oct 19, 2001·Proceedings of the National Academy of Sciences of the United States of America·M DelledonneC Lamb
Oct 19, 2001·Proceedings of the National Academy of Sciences of the United States of America·J MoskovitzE R Stadtman
Oct 20, 2001·Current Opinion in Plant Biology·E P Beers, J M McDowell
Jan 5, 2002·Proceedings of the National Academy of Sciences of the United States of America·Miguel Angel TorresJonathan D G Jones
Jan 10, 2002·Biochemical and Biophysical Research Communications·Jackob MoskovitzEarl R Stadtman
Feb 28, 2002·Proceedings of the National Academy of Sciences of the United States of America·Hongyu RuanStephen H Heinemann
Apr 4, 2002·Proceedings of the National Academy of Sciences of the United States of America·Gregory V KryukovVadim N Gladyshev
Apr 9, 2002·Nature Structural Biology·W Todd LowtherBrian W Matthews
Jun 13, 2002·Molecular Plant-microbe Interactions : MPMI·Sang Jik LeeChee Hark Harn
Jul 30, 2002·The Journal of Biological Chemistry·R Abhilash KumarVadim N Gladyshev
Sep 11, 2002·The Plant Journal : for Cell and Molecular Biology·Yule LiuS P Dinesh-Kumar
Jun 26, 2003·Nucleic Acids Research·Ramu ChennaJulie D Thompson
Oct 29, 2003·Antioxidants & Redox Signaling·Earl R StadtmanRodney L Levine
Jun 1, 1997·Annual Review of Plant Physiology and Plant Molecular Biology·Chris Lamb, Richard A. Dixon
Sep 16, 2004·The Plant Cell·Hye Sun ChoHyun-Sook Pai
Sep 21, 2004·Annual Review of Plant Biology·Klaus Apel, Heribert Hirt
Feb 1, 2005·Biochimica Et Biophysica Acta·Earl R StadtmanRodney L Levine
Feb 1, 2005·Biochimica Et Biophysica Acta·Benjamin EzratyFrédéric Barras
Aug 1, 1987·Proceedings of the National Academy of Sciences of the United States of America·P R EbertG An
Apr 11, 2006·Annual Review of Phytopathology·L C van LoonC M J Pieterse
Oct 13, 2006·Photosynthesis Research·Nicolas RouhierPascal Rey

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Citations

Jul 19, 2013·Journal of Plant Physiology·Hatem BoubakriIsabelle Soustre-Gacougnolle
Jun 19, 2012·BMC Genomics·Kerstin BüchelTorsten Meiners
Jan 15, 2014·Biochimica Et Biophysica Acta·Adrian Drazic, Jeannette Winter
Apr 6, 2011·Plant Physiology and Biochemistry : PPB·Priya Padmanabhan, Shivendra V Sahi
Nov 2, 2013·Mass Spectrometry Reviews·Bart Ghesquière, Kris Gevaert
Jun 1, 2014·Journal of Plant Physiology·Sang-Keun OhSuk-Yoon Kwon
Feb 14, 2015·Biochimica Et Biophysica Acta·Nicolas RouhierPascal Rey
Aug 17, 2012·Plant Signaling & Behavior·Huajian ZhangZhengguang Zhang
Nov 19, 2013·Biochemical and Biophysical Research Communications·Sang-Keun OhDoil Choi
Feb 13, 2013·Proceedings of the National Academy of Sciences of the United States of America·Emilie ChâtelainFrançoise Montrichard
Jun 26, 2014·Journal of Experimental Botany·Shu-Hong LeeMing-Tsair Chan
Sep 26, 2014·Planta·Hyong Woo Choi, Byung Kook Hwang
Mar 24, 2016·Phytopathology·Bode OlukoluPeter John Balint-Kurti
Feb 12, 2017·Biochimica Et Biophysica Acta. General Subjects·Guoxiang JiangYueming Jiang
Apr 12, 2020·International Journal of Molecular Sciences·Mario ParisiPasquale Tripodi
Jan 7, 2021·International Journal of Molecular Sciences·Natalia WojciechowskaEwa M Kalemba
Dec 6, 2020·International Journal of Molecular Sciences·Natalia WojciechowskaEwa M Kalemba

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