PMID: 20628445Jul 16, 2010Paper

Can autism be triggered by acetaminophen activation of the endocannabinoid system?

Acta Neurobiologiae Experimentalis
Stephen T Schultz

Abstract

Acetaminophen use in children has been associated with increased autism risk. Recent evidence suggests that acetaminophen's analgesic actions result from activation of the endocannabinoid system, and activation of this system can have neuromodulatory consequences during development. This investigation was performed to determine if there is evidence to support the hypothesis that acetaminophen use can trigger autism by activation of the endocannabinoid system.

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