Can contamination of a patient's allograft be traced back to the allograft donor?

Journal of Burn Care & Research : Official Publication of the American Burn Association
Alice N NeelyRichard J Kagan

Abstract

Cultures of allograft sites on burn patients occasionally show microbes that were not previously cultured from that patient. Our purpose was to determine 1) if microbes on allograft sites could have been transferred to the burn patient from the allograft donor and 2) if microbial transfer is different if the allograft was fresh or frozen. All allografts were cultured by the skin bank after recovery (pre-antimicrobial) and after the skin had been in an antimicrobial solution (post-antimicrobial). These culture results were compared with the results of cultures taken at the hospital from the allograft sites of burn patients. All allograft recipients at the burn hospital during 2005 were included in this Institutional Review Board approved study. Sixty-one donors provided 143 allografts for 38 patients. From the 61 donors, 114 precultures were taken; 19.5% were positive for at least one organism. Only 6.8% of 118 post-antimicrobial cultures were positive. Of the 143 allografts on burn patients, 111 were used fresh and 32 had been cryopreserved. During dressing changes, 124 cultures were taken from sites that received fresh allograft and 27 from sites that received frozen; 54.8% of cultures from fresh allograft sites and 41.5% from...Continue Reading

References

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Citations

Aug 16, 2016·Cell and Tissue Banking·C JohnstonUNKNOWN Bioburden Steering Committee and Skin Working group
May 25, 2010·International Wound Journal·Andrew J LindfordVirve Koljonen
Oct 17, 2015·Burns : Journal of the International Society for Burn Injuries·John L FletcherRodney K Chan
Sep 27, 2018·BMC Microbiology·Karine Lena MeneghettiGertrudes Corção
Mar 26, 2011·Journal of Burn Care & Research : Official Publication of the American Burn Association·Tianjun SunHongming Yang
Jan 4, 2017·Journal of Burn Care & Research : Official Publication of the American Burn Association·Jordan SpradbrowJeannie Callum
Aug 14, 2020·Burns : Journal of the International Society for Burn Injuries·Nicolas GermainPhilippe Marchetti

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