Can deep transcranial magnetic stimulation (DTMS) be used to treat substance use disorders (SUD)? A systematic review

BMC Psychiatry
Karina Karolina KedziorMaria Schuchinsky

Abstract

Deep transcranial magnetic stimulation (DTMS) is a non-invasive method of stimulating widespread cortical areas and, presumably, deeper neural networks. The current study assessed the effects of DTMS in the treatment of substance use disorders (SUD) using a systematic review. Electronic literature search (PsycInfo, Medline until April 2017) identified k = 9 studies (k = 4 randomized-controlled trials, RCTs, with inactive sham and k = 5 open-label studies). DTMS was most commonly applied using high frequency/intensity (10-20 Hz/100-120% of the resting motor threshold, MT) protocols for 10-20 daily sessions in cases with alcohol, nicotine or cocaine use disorders. The outcome measures were craving and dependence (according to standardized scales) or consumption (frequency, abstinence or results of biological assays) at the end of the daily treatment phases and at the last follow-up. Acute and longer-term (6-12 months) reductions in alcohol craving were observed after 20 sessions (20 Hz, 120% MT) relative to baseline in k = 4 open-label studies with comorbid SUD and major depressive disorder (MDD). In k = 2 RCTs without MDD, alcohol consumption acutely decreased after 10-12 sessions (10-20 Hz, 100-120% MT) relative to baseline or ...Continue Reading

References

Apr 1, 1989·Journal of Behavioral Medicine·K O Fagerstrom, N G Schneider
Mar 1, 1996·Drug and Alcohol Dependence·D E McMillan, K Gilmore-Thomas
Feb 1, 1960·Journal of Neurology, Neurosurgery, and Psychiatry·M HAMILTON
Mar 29, 2005·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·Abraham ZangenMark Hallett
Apr 18, 2008·Nicotine & Tobacco Research : Official Journal of the Society for Research on Nicotine and Tobacco·Stephen J HeishmanWallace B Pickworth
Jul 23, 2009·BMJ : British Medical Journal·David MoherUNKNOWN PRISMA Group
Nov 17, 2009·Neuroscience and Biobehavioral Reviews·Jodie Feil, Abraham Zangen
Oct 20, 2011·BMJ : British Medical Journal·Julian P T HigginsUNKNOWN Cochrane Statistical Methods Group
Aug 7, 2013·Neuroscience and Biobehavioral Reviews·Jochem M JansenAnna E Goudriaan
Sep 3, 2013·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·Yiftach RothMenashe Zaaroor
Aug 21, 2014·The World Journal of Biological Psychiatry : the Official Journal of the World Federation of Societies of Biological Psychiatry·Paolo GirardiGloria Angeletti
Feb 7, 2015·World Psychiatry : Official Journal of the World Psychiatric Association (WPA)·Yechiel LevkovitzAbraham Zangen
Mar 3, 2015·Canadian Journal of Physiology and Pharmacology·Marco CeccantiMauro Ceccanti
Sep 29, 2015·Alcoholism, Clinical and Experimental Research·Hollis C KarolyKent E Hutchison
Feb 2, 2016·Journal of Psychiatric Research·Karina Karolina KedziorMarcelo T Berlim
Feb 6, 2016·Annals of the New York Academy of Sciences·Katharine DunlopJonathan Downar
Jun 1, 2016·Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology·Michael C Salling, Diana Martinez
Sep 8, 2016·Expert Review of Medical Devices·Aron TendlerAbraham Zangen
Apr 10, 2017·European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology·Giovanni AddoloratoDaniela Di Giuda
Sep 28, 2017·Nature Reviews. Neuroscience·Marco DianaAntonello Bonci

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Citations

Nov 12, 2019·Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology·Irene PeriniMarkus Heilig
Dec 5, 2019·Physics in Medicine and Biology·Jose Gomez-TamesShoogo Ueno
Jul 1, 2020·European Archives of Psychiatry and Clinical Neuroscience·Carlota de MiquelAlkomiet Hasan
Feb 16, 2021·Neuroscience and Biobehavioral Reviews·Khushbu AgarwalPaule Valery Joseph

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