Can dietary self-reports usefully complement blood concentrations for estimation of micronutrient intake and chronic disease associations?

The American Journal of Clinical Nutrition
Ross L PrenticeJohanna W Lampe

Abstract

We recently presented associations between serum-based biomarkers of carotenoid and tocopherol intake and chronic disease risk in a Women's Health Initiative (WHI) Measurement Precision subcohort (n = 5488). Questions remain as to whether self-reported dietary data can usefully augment such biomarkers or can be calibrated using biomarkers for reliable disease association estimation in larger WHI cohorts. The aims were to examine the potential of FFQ data to explain intake variation in a WHI Feeding Study and to compare association parameter estimates and their precision from studies based on biomarker-calibrated FFQ intake in larger WHI cohorts, with those previously presented. Serum-based intake measures were augmented by using FFQ data in a WHI Feeding Study (n = 153). Corresponding calibration equations were generated, both in a companion Nutritional Biomarker Study (n = 436) and in the previously mentioned subcohort (n = 5488), by regressing these intake measures on dietary data and participant characteristics, for α- and β-carotene, lutein plus zeaxanthin, and α-tocopherol. The supplemental value of FFQ data was considered by examining the fraction of feeding study intake variation explained by these regression models. Cal...Continue Reading

References

Apr 7, 1999·Annals of Epidemiology·R E PattersonT Agurs-Collins
Jan 24, 2003·The American Journal of Clinical Nutrition·Myron GrossDavid R Jacobs
Mar 4, 2003·The Journal of Nutrition·Sheila A Bingham
Oct 25, 2003·Annals of Epidemiology·J David CurbUNKNOWN WHI Morbidity and Mortality Committee
Jan 6, 2005·American Journal of Epidemiology·Rulla M TamimiDavid J Hunter
Jun 19, 2008·Clinical Trials : Journal of the Society for Clinical Trials·Karen L MargolisUNKNOWN Women Health Initiative Investigators
Feb 26, 2013·American Journal of Epidemiology·Marian L NeuhouserRoss L Prentice
Dec 30, 2016·The American Journal of Clinical Nutrition·Johanna W LampeRoss L Prentice

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Citations

May 30, 2020·The American Journal of Clinical Nutrition·Christina C Dahm

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