Can Elastography Predict Growth of Incidental Thyroid Nodules? A Pilot Two-Year Follow-Up Study

Ultrasonic Imaging
Anne KrejbjergPeter Laurberg

Abstract

The objective of this study was to examine the ultrasonography (US) and ultrasound elastography (USE) features of thyroid incidentalomas in a population exposed to iodine deficiency and to investigate whether baseline elasticity scores (ES) predicted changes in thyroid nodule US characteristics. We conducted a two-year follow-up pilot study of thyroid incidentalomas by US and USE. One sonographer performed the US and USE examination on the same apparatus at baseline and at follow-up. We evaluated 83 incidental thyroid nodules detected in a population study. The follow-up period saw no change in median thyroid nodule diameter (p = 0.18) or in the prevalence of thyroid nodule US characteristics (hypoechoic: p = 0.05; solid nodule: p = 1.00; microcalcifications: p = 0.55). Individual changes in thyroid nodule diameter (>20%) were seen in 23% (11% had decreased, and 12% had increased in diameter). Changes in ES were frequently observed; 37% changed from ES A + B to ES C + D, and 27% changed from ES C + D to ES A + B. In a multivariate logistic regression model, we found no association between baseline ES and individual changes in nodule size. In an area with mild iodine deficiency and a high prevalence of thyroid nodules, thyroid U...Continue Reading

References

Jul 8, 1988·Deutsche medizinische Wochenschrift·R GutekunstP Pfannenstiel
Jan 1, 1994·Thyroid : Official Journal of the American Thyroid Association·F Delange
Dec 14, 1999·Thyroid : Official Journal of the American Thyroid Association·N KnudsenP Laurberg
Aug 25, 2005·Radiology·Andrej LyshchikKaori Togashi
Oct 20, 2005·Ultrasonic Imaging·A LyshchikK Togashi
Nov 11, 2005·Thyroid : Official Journal of the American Thyroid Association·V F H BrauerR Paschke
Nov 24, 2006·Clinical Endocrinology·Murat Faik ErdoganGurbuz Erdogan
May 31, 2007·The Journal of Clinical Endocrinology and Metabolism·T RagoP Vitti
May 10, 2008·Thyroid : Official Journal of the American Thyroid Association·Carmela AsteriaAdele Zoppo
May 23, 2008·Ultraschall in der Medizin : Organ der Deutschen Gesellschaft für Ultraschall in der Medizin, [der] Österreichischen Gesellschaft für Ultraschall in der Medizin, [der] Schweizerischen Gesellschaft für Ultraschall in Medizin und Biologie·L RubaltelliR Stramare
Jun 24, 2009·Journal of Ultrasound in Medicine : Official Journal of the American Institute of Ultrasound in Medicine·Yurong HongZhiyan Luo
Jul 16, 2010·Langenbeck's Archives of Surgery·Christian VorländerRobert A Wahl
Jan 17, 2012·Annals of Surgical Oncology·Hee Jung MoonJin Young Kwak
Nov 28, 2012·Cancer Epidemiology·Stefano Christian LonderoChristian Godballe
Feb 19, 2013·European Journal of Endocrinology·Gilles RussLaurence Leenhardt
Jul 23, 2014·Best Practice & Research. Clinical Endocrinology & Metabolism·Allan CarléPeter Laurberg
Sep 19, 2014·The Journal of Clinical Endocrinology and Metabolism·Anne KrejbjergPeter Laurberg
Jan 24, 2015·Journal of Ultrasound in Medicine : Official Journal of the American Institute of Ultrasound in Medicine·Anne KrejbjergPeter Laurberg
Mar 4, 2015·JAMA : the Journal of the American Medical Association·Cosimo DuranteSebastiano Filetti

❮ Previous
Next ❯

Methods Mentioned

BETA
biopsy

Software Mentioned

STATA

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Schweizerische Medizinische Wochenschrift. Supplementum
F Bandhauer
Journal of Ultrasound in Medicine : Official Journal of the American Institute of Ultrasound in Medicine
Anne KrejbjergPeter Laurberg
BMJ : British Medical Journal
Chirag N PatelAndrew F Scarsbrook
© 2021 Meta ULC. All rights reserved