PMID: 8971363Oct 1, 1996Paper

Can elevated chromium induce somatopsychic responses?

Biological Trace Element Research
I LovrincevicD M Grace

Abstract

The possible somatopsychological effects of chromium (Cr) was investigated in a population of patients, from a surgical ward of our hospital, who required total parenteral nutrition (TPN) solutions, and who became exposed to various amounts of this metal from this treatment. The study involved a questionnaire as well as biochemical tests which included serum Cr and other selected trace metals. The renal status for all eligible patients was within normal parameters. The patient population varied in age, pathology, surgical treatment, and duration on TPN. The results showed that every patient who received TPN had an increased serum Cr level; some increases were up to 50-fold above the normal reference level for serum Cr. Although statistical analysis failed to show any significant statistical relationship between an increased serum Cr and the investigated somatopsychological disturbances, this effect cannot be ruled out since one case did show all the dream disturbances. Considering these cases, the action of sedative medications that may suppress the effects of Cr, cannot be ruled out. As Cr(III) may be potentially genotoxic at high concentrations, infusion of this metal over long time periods should be avoided. Supplementation ...Continue Reading

References

Feb 2, 1979·JAMA : the Journal of the American Medical Association·H FreundJ E Fischer
Jan 1, 1992·Biological Trace Element Research·V Ducros
Nov 1, 1990·JPEN. Journal of Parenteral and Enteral Nutrition·Y ItoM E Shils
Jun 1, 1986·Digestive Diseases and Sciences·R O BrownW D Heizer
Mar 1, 1986·Journal of Neurology, Neurosurgery, and Psychiatry·S Duckett
Feb 1, 1968·Metabolism: Clinical and Experimental·R A LevineR J Doisy
Mar 1, 1968·The American Journal of Clinical Nutrition·L L HopkinsA S Majaj
Mar 1, 1994·Molecular Carcinogenesis·L C BridgewaterS R Patierno
Apr 1, 1994·Biometals : an International Journal on the Role of Metal Ions in Biology, Biochemistry, and Medicine·B GulanowskiJ Urban
Jan 1, 1993·Critical Reviews in Toxicology·M D CohenM Costa
Jul 1, 1993·Journal of Pediatric Gastroenterology and Nutrition·D BougleJ F Duhamel
May 1, 1986·Clinical Nutrition : Official Journal of the European Society of Parenteral and Enteral Nutrition·A ShenkinM H Irving

❮ Previous
Next ❯

Citations


❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.