Can homeopathically prepared mercury cause symptoms in healthy volunteers? A randomized, double-blind placebo-controlled trial

The Journal of Alternative and Complementary Medicine : Research on Paradigm, Practice, and Policy
A J VickersM Heger

Abstract

To pilot a method for determining whether homeopathically prepared mercury causes more symptoms (a "drug proving") in healthy volunteers than placebo. One hundred and eighteen (118) healthy volunteers ages 18 to 65 were recruited by local advertising. Subjects unfamiliar with homeopathy undertook a 1-week single-blind placebo run-in, a 1-week of double-blind, randomized treatment on either homeopathically prepared mercury 12C or placebo, and a third week of placebo run-out. Each day, symptoms were recorded on a checklist that included both true mercury symptoms and symptoms not expected to be caused by mercury (false symptoms). Additional symptoms were assessed by open reporting. Outcome was assessed by calculating a score for each day as the number of true symptoms minus the number of false symptoms. The mean score during placebo was then subtracted from the mean score for weeks two and three of the trial. Fourteen (14) subjects dropped out during placebo run-in. The remaining 104 completed the trial. Baseline comparability was good. Mean difference score was -0.125 (SD 3.47) for mercury and -0.221 (SD 3.01) for placebo (p > 0.2). No significant differences between groups were found for the number of subjects meeting predefine...Continue Reading

Citations

Jun 30, 2005·Forschende Komplementärmedizin und klassische Naturheilkunde = Research in complementary and natural classical medicine·Sarah Brien, George Lewith
Dec 19, 2015·Homeopathy : the Journal of the Faculty of Homeopathy·Harald Walach, Michael Teut
Aug 26, 2004·British Journal of Clinical Pharmacology·Edward Shalts, Samuel Shiflett
Jul 16, 2003·Allergy·B Niggemann, C Grüber
Jul 4, 2006·Homeopathy : the Journal of the Faculty of Homeopathy·G DominiciG Pitari
Feb 6, 2004·Revista do Hospital das Clínicas·Renan Moritz V Rodrigues Almeida
Feb 18, 2004·International Journal of Circumpolar Health·Dennis G FisherMichele M Wood

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