PMID: 6106521Apr 5, 1980Paper

Can insulin-treated diabetics be given beta-adrenergic blocking drugs?

British Medical Journal
A H BarnettP J Watkins

Abstract

Lack of awareness of hypoglycaemia leading to loss of consciousness is a serious problem in some insulin-treated diabetics, and beta-blocking drugs may increase this hazard. A prospective study was therefore carried out over eight months to determine the incidence of hypoglycaemic episodes in 50 insulin-treated diabetics taking beta-blockers, as compared with 100 diabetic controls matched for age, sex, and duration of diabetes. The incidence of loss of consciousness from hypoglycaemia was the same in both groups and was unrelated to the dose of beta-blocking drug used. Five patients taking beta-blockers and 10 controls had episodes of unconsciousness, but four of these patients taking beta-blockers had had similar episodes in the two years preceding treatment. It is concluded that beta-blocking drugs are generally safe in insulin-treated diabetics and that hypoglycaemic unconsciousness resulting from their use is rare.

Associated Clinical Trials

May 22, 2017·Anu SharmaAnu Sharma

References

Jul 31, 1976·British Medical Journal·S P Deacon, D Barnett
Aug 31, 1978·The New England Journal of Medicine·L Strom
Dec 24, 1966·Lancet·M N KotlerA H Rubenstein
Jan 1, 1963·Diabetes·K E SUSSMANA MARBLE

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Citations

Apr 1, 1993·Aging : Clinical and Experimental Research·M StepkaA Czyzyk
Jul 25, 1985·The New England Journal of Medicine·P E Cryer, J E Gerich
Sep 1, 1990·Diabetic Medicine : a Journal of the British Diabetic Association·D A HepburnB M Frier
Feb 22, 1986·British Medical Journal·G V SawleD A Heath
Apr 2, 1988·British Medical Journal·R E Ferner, H A Neil
Jul 1, 1985·Postgraduate Medical Journal·A D Struthers
Dec 13, 1980·British Medical Journal
Oct 15, 2010·Drug Safety : an International Journal of Medical Toxicology and Drug Experience·Chaker Ben SalemKamel Bouraoui
Apr 1, 2011·Journal of the American Medical Directors Association·Yael Dinur SchejterZvi Ackerman
Nov 9, 2015·Autonomic Neuroscience : Basic & Clinical·Ana Barbara Alves-WagnerUbiratan Fabres Machado
Feb 1, 1988·Diabetes/metabolism Reviews·S A AmielR S Sherwin
Mar 1, 1988·Diabetes/metabolism Reviews·J E Gerich, P J Campbell
Jul 1, 1986·Diabetic Medicine : a Journal of the British Diabetic Association·C M Ritchie, A B Atkinson
Nov 10, 1983·The American Journal of Cardiology·S H Taylor
Mar 15, 2016·Liver International : Official Journal of the International Association for the Study of the Liver·Laure ElkriefRichard Moreau
Jul 17, 2001·Journal of Internal Medicine·P T Sawicki, A Siebenhofer
Nov 1, 1985·Hypertension·B N TrostC Beretta-Piccoli
Jun 1, 2017·Hypertension·Tetsuro TsujimotoHiroshi Kajio
Jun 1, 1991·Journal of Clinical Pharmacy and Therapeutics·C M Florkowski, M J Kendall
Feb 1, 1988·Diabetes/metabolism Reviews·R T FrizzellA D Cherrington
May 1, 1985·Annals of Neurology·R Malouf, J C Brust
Aug 5, 2011·Diabetic Medicine : a Journal of the British Diabetic Association·A H Barnett
Jul 28, 2016·Diabetes Care·Tetsuro TsujimotoHiroshi Kajio
Jan 1, 1989·Renal Failure·H E EliahouD Cohen
Sep 1, 1986·Medical Toxicology·R V Lewis, D G McDevitt

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