Can local anesthesia with ropivacaine provide postoperative analgesia in extraction of impacted mandibular third molars? A randomized clinical trial.

Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology
Klinger de Souza AmorimLiane Maciel de Almeida Souza

Abstract

The aim of this study was to compare the local anesthesia efficacy of ropivacaine 0.75% compared to lidocaine 2% with 1:100,000 epinephrine for postoperative analgesia following extraction of impacted mandibular third molars. In this randomized, double-blind crossover clinical trial, 30 participants underwent surgical removal of bilateral impacted mandibular third molars under local anesthesia using ropivacaine 0.75% or lidocaine 2% with 1:100,000 epinephrine. The pain was recorded on a visual analog scale at 4, 8, 12, 24, and 48 h postoperatively. The use of analgesics and the presence of adverse effects were recorded. The duration of soft tissue anesthesia in the ropivacaine group was significantly longer than that in the lidocaine group. The lidocaine group recorded significantly higher visual analog scale scores at all postoperative time intervals, except in the final 48-h period. Analgesic use was higher in the lidocaine group. Rescue medication was used by 2 patients in each group (6.7%). Significantly more postoperative bleeding was seen in the ropivacaine group. Ropivacaine 0.75% injection before the surgical procedure may be associated with preventive analgesia for extraction of impacted mandibular third molars.

References

Jan 1, 1992·Free Radical Biology & Medicine·C F Babbs
Apr 1, 1994·The Journal of Pharmacy and Pharmacology·R K GoelA Bennett
Dec 31, 1997·Inflammation Research : Official Journal of the European Histamine Research Society ... [et Al.]·T MartinssonC J Dalsgaard
Mar 24, 1998·Journal of Cardiothoracic and Vascular Anesthesia·R M SmileyD A Schwinn
Dec 18, 2001·Canadian Journal of Anaesthesia = Journal Canadien D'anesthésie·D J KellyS J Brull
Sep 7, 2002·Journal of Oral and Maxillofacial Surgery : Official Journal of the American Association of Oral and Maxillofacial Surgeons·Malin Ernberg, Sigvard Kopp
Feb 25, 2005·Anesthesia and Analgesia·Cliff K-S OngBrian J Jenkins
Jul 14, 2005·Current Opinion in Otolaryngology & Head and Neck Surgery·Margaret A Chen, Terence M Davidson
May 26, 2006·Anesthesia Progress·Eman El-Sharrawy, John A Yagiela
May 27, 2006·Head & Face Medicine·Waseem JerjesColin Hopper
Aug 7, 2008·The Journal of the American Dental Association·Mary TavaresUNKNOWN Soft Tissue Anesthesia Reversal Group
Feb 19, 2009·Pain Medicine : the Official Journal of the American Academy of Pain Medicine·Seetharaman HariharanSenthilkumar Raju
Apr 21, 2009·Journal of Oral and Maxillofacial Surgery : Official Journal of the American Association of Oral and Maxillofacial Surgeons·Fábio Ricardo Loureiro SatoMárcio de Moraes
Dec 17, 2009·International Journal of Oral and Maxillofacial Surgery·B M B BrkovicD Stojic
May 18, 2011·Medical Principles and Practice : International Journal of the Kuwait University, Health Science Centre·Ziad MalkawiAmeen Khraisat
May 21, 2011·Revista brasileira de anestesiologia·Maria Cristina Simões de AlmeidaAna Laura Colle Kauling
Jun 30, 2011·Indian Journal of Anaesthesia·Gaurav Kuthiala, Geeta Chaudhary
May 7, 2014·The Journal of Craniofacial Surgery·Marco MozzatiCarmen Mortellaro

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.