Can MRI quantification help evaluate stroke age?

Journal of Neuroradiology. Journal De Neuroradiologie
Samuel EmeriauLaurent Pierot

Abstract

Diffusion-weighted imaging (DWI) fluid-attenuated inversion recovery (FLAIR) mismatch has a proven ability to estimate stroke-to-magnetic resonance imaging (MRI) delay. We evaluated the possibility of enhancing this estimation by quantifying MRI (DWI and FLAIR) signals, and compared this approach to the visual evaluation of DWI-FLAIR mismatch. This retrospective study included 194 patients presenting an ischemic stroke in the middle cerebral artery territory that had been explored with 3T MRI within 12h. According to the study design, written informed consent was waived and patient information was anonymized and de-identified prior to analysis. DWI-FLAIR mismatch was visually estimated by two radiologists and a quantification of MRI signals based on a manual segmentation of stroke lesion volume was performed. Using their receiver operating curve and area under the curve (AUC), we identified the variables of MRI quantification that were predictive of stroke-to-MRI delay, then compared their performance against visual classification. The quantitative variables identified as predictive of stroke-to-MRI delay were: 1st quartile, 3rd quartile and median values of B0; 1st quartile, 3rd quartile, median and relative values of B1000; 1...Continue Reading

References

Oct 18, 2005·Journal of Neurology, Neurosurgery, and Psychiatry·P A BarberUNKNOWN ASPECTS Study Group
Mar 11, 2008·Journal of Neuroradiology. Journal De Neuroradiologie·K O LövbladL Sekoranja
May 15, 2008·Cerebrovascular Diseases·UNKNOWN European Stroke Organisation (ESO) Executive Committee, UNKNOWN ESO Writing Committee
Apr 10, 2009·AJNR. American Journal of Neuroradiology·P G Kranz, J D Eastwood
Dec 26, 2009·Stroke; a Journal of Cerebral Circulation·Martin EbingerJochen B Fiebach
Nov 1, 2011·Journal of Neurology·Annerose ZieglerStefanie Leistner
Dec 24, 2011·AJR. American Journal of Roentgenology·Sangam G KanekarRebecca Roller
Oct 11, 2012·Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism·Bastian ChengUNKNOWN STIR and VISTA Imaging Investigators
Oct 25, 2012·Stroke; a Journal of Cerebral Circulation·Dong-Wha KangJong S Kim
Nov 8, 2012·Stroke; a Journal of Cerebral Circulation·Chelsea S Kidwell
Mar 25, 2014·PloS One·Vince I MadaiJan Sobesky
Dec 4, 2014·Journal of Neuroradiology. Journal De Neuroradiologie·Karl-Olof LövbladRoman Sztajzel

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