Can obesity and physical activity predict outcomes of elective knee or hip surgery due to osteoarthritis? A meta-analysis of cohort studies

BMJ Open
Daniel PozzobonManuela L Ferreira

Abstract

The aim of this study was to systematically review the literature to identify whether obesity or the regular practice of physical activity are predictors of clinical outcomes in patients undergoing elective hip and knee arthroplasty due to osteoarthritis. Systematic review and meta-analysis. A systematic search was performed on the Medline, CINAHL, EMBASE and Web of Science electronic databases. Longitudinal cohort studies were included in the review. To be included, studies needed to have assessed the association between obesity or physical activity participation measured at baseline and clinical outcomes (ie, pain, disability and adverse events) following hip or knee arthroplasty. Two independent reviewers extracted data on pain, disability, quality of life, obesity, physical activity and any postsurgical complications. 62 full papers were included in this systematic review. From these, 31 were included in the meta-analyses. Our meta-analysis showed that compared to obese participants, non-obese participants report less pain at both short term (standardised mean difference (SMD) -0.43; 95% CI -0.67 to -0.19; P<0.001) and long term post-surgery (SMD -0.36; 95% CI -0.47 to -0.24; P<0.001), as well as less disability at long ter...Continue Reading

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Citations

Apr 7, 2020·The Journal of Bone and Joint Surgery. American Volume·Samantha M MeintsKristin L Schreiber
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Sep 5, 2021·The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences·Thomas LaskowRavi Varadhan

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Methods Mentioned

BETA
total hip arthroplasty
hip arthroplasty
total

Software Mentioned

Comprehensive Meta - Analysis Meta - Analysis
STATA

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