Can one hear the shape of a population history?

Theoretical Population Biology
Junhyong KimNathan Ross

Abstract

Reconstructing past population size from present day genetic data is a major goal of population genetics. Recent empirical studies infer population size history using coalescent-based models applied to a small number of individuals. Here we provide tight bounds on the amount of exact coalescence time data needed to recover the population size history of a single, panmictic population at a certain level of accuracy. In practice, coalescence times are estimated from sequence data and so our lower bounds should be taken as rather conservative.

References

Feb 19, 2004·Biometrics·Wenqing He, Jerald F Lawless
Feb 11, 2005·Molecular Biology and Evolution·A J DrummondO G Pybus
Jul 29, 2005·Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences·Gilean A T McVean, Niall J Cardin
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Oct 30, 2012·American Journal of Human Genetics·Pier Francesco PalamaraItsik Pe'er

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Citations

Apr 8, 2017·Journal of Theoretical Biology·Kris V Parag, Oliver G Pybus
Feb 7, 2019·Systematic Biology·Kris V Parag, Oliver G Pybus
Aug 8, 2019·Proceedings of the National Academy of Sciences of the United States of America·Matthias SteinrückenYun S Song
Dec 4, 2019·Journal of Computational Biology : a Journal of Computational Molecular Cell Biology·Younhun KimGovind Ramnarayan
Jun 10, 2015·Proceedings of the National Academy of Sciences of the United States of America·Jonathan Terhorst, Yun S Song

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