Can oral sucrose reduce the pain and distress associated with screening for retinopathy of prematurity?

Journal of Perinatology : Official Journal of the California Perinatal Association
Joanna GrabskaVictor Herson

Abstract

Infants undergoing eye exams to screen for retinopathy of prematurity (ROP) demonstrate physiologic and behavioral manifestations of pain and distress. Oral sucrose has analgesic properties that might reduce these effects. To determine the efficacy of oral sucrose in reducing the pain/distress of eye exams for ROP. A total of 32 infants about to undergo ROP screening exams received either oral sucrose [S] (N=16) or sterile water [C] (N=16) in a randomized, prospective and blinded fashion. Outcome measures included HR, RR, O(2) saturation, BP, pain (premature infant pain profile) and percent of time spent crying during the eye exam. The groups were similar in GA (weeks) (28+/-1.6), BW (kg) (1.04+/-0.26), postnatal age (days) 50.8+/-20.3, and study weight (kg) 1.88+/-0.40). Both groups demonstrated significant increases in HR, BP, and pain score in response to the exam. Infants in both groups spent the majority of time actively crying during the exam ([S] 53+/-35% vs [C] 63+/-31%. Infants receiving [S] showed a small but significant drop in O(2) saturation. No significant differences were seen between groups in physiologic or behavioral responses to the eye exam. Oral [S] was not effective in reducing pain/distress from the ROP s...Continue Reading

References

Jul 1, 1984·The Journal of Pediatrics·S Isenberg, S Everett
May 1, 1996·The British Journal of Ophthalmology·D E LawsD Clark
Mar 1, 1996·The Clinical Journal of Pain·B StevensA Taddio
Jan 10, 1998·The British Journal of Ophthalmology·M SlevinM O'Keefe
Feb 15, 2001·Archives of Pediatrics & Adolescent Medicine·K J Anand, UNKNOWN International Evidence-Based Group for Neonatal Pain

❮ Previous
Next ❯

Citations

Nov 30, 2011·Advances in Neonatal Care : Official Journal of the National Association of Neonatal Nurses·Anita J MitchellPaula K Roberson
Jan 24, 2006·Archives of Disease in Childhood. Fetal and Neonatal Edition·E M BoyleN McIntosh
Jun 7, 2011·Journal of AAPOS : the Official Publication of the American Association for Pediatric Ophthalmology and Strabismus·Yogavijayan KandasamyLeo Hartley
Jan 10, 2012·Journal of Pediatric Nursing·Manal Ibrahim KassabMaralyn Foureur
Aug 26, 2010·Journal of AAPOS : the Official Publication of the American Association for Pediatric Ophthalmology and Strabismus·Yi Ning J StrubeBrian W Arthur
Oct 9, 2009·Anales de pediatría : publicación oficial de la Asociación Española de Pediatría (A.E.P.)·J R Castro CondeUNKNOWN Comisión de Estándares de la Sociedad Española de Neonatología
Aug 12, 2009·Survey of Ophthalmology·Grace M RichterMichael F Chiang
Apr 29, 2009·The Journal of Pain : Official Journal of the American Pain Society·Denise HarrisonLinda Johnston
Feb 12, 2011·Journal of Clinical Nursing·Emma Olsson, Mats Eriksson
Feb 17, 2015·Indian Journal of Pediatrics·Manisha KatariaParul Chawla Gupta
Mar 7, 2015·International Journal of Clinical Pharmacy·Mark Shen, Gladys El-Chaar
Mar 25, 2017·Journal of AAPOS : the Official Publication of the American Association for Pediatric Ophthalmology and Strabismus·David L RogersUNKNOWN e-ROP Cooperative Group
Dec 19, 2013·Revista da Escola de Enfermagem da U S P·Laiane Medeiros RibeiroCarmen Gracinda Silvan Scochi
Jul 25, 2017·Pediatric Research·Christoph BührerJanet Berrington
Jul 29, 2018·Acta Paediatrica·Anna PirelliUNKNOWN Pain Study Group of the Italian Society of Neonatology
Jul 16, 2016·The Cochrane Database of Systematic Reviews·Bonnie StevensAllyson Shorkey
Feb 4, 2012·Revista gaúcha de enfermagem·Caroline de Oliveira AlvesTatiana Silva Tavares
Feb 3, 2012·Critical Care Nurse·Tracy Ann Pasek, Jessica Marie Huber
Apr 18, 2017·Breastfeeding Medicine : the Official Journal of the Academy of Breastfeeding Medicine·Ayşe Şener Taplak, Emine Erdem
Mar 2, 2006·The Journal of Perinatal & Neonatal Nursing·Karen C D'Apolito
Jun 23, 2009·Advances in Neonatal Care : Official Journal of the National Association of Neonatal Nurses·Haifa A Samra, Jacqueline M McGrath
Sep 12, 2007·Advances in Neonatal Care : Official Journal of the National Association of Neonatal Nurses·UNKNOWN American Academy of PediatricsUNKNOWN Fetus and Newborn Committee
May 20, 2016·Advances in Neonatal Care : Official Journal of the National Association of Neonatal Nurses·Kim Francis
Feb 14, 2019·Journal of Perinatology : Official Journal of the California Perinatal Association·John B C TanDanilyn M Angeles
Oct 17, 2020·Journal of Perinatology : Official Journal of the California Perinatal Association·Dan Ni WangStephanie A Dotchin
Jul 17, 2021·Journal of AAPOS : the Official Publication of the American Association for Pediatric Ophthalmology and Strabismus·Shagun K BhatiaShira L Robbins
Aug 3, 2017·Journal of Obstetric, Gynecologic, and Neonatal Nursing : JOGNN·Şirin Bozlak, Gülümser Dolgun

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.