Can platelet-rich plasma have a role in Achilles tendon surgical repair?

Knee Surgery, Sports Traumatology, Arthroscopy : Official Journal of the ESSKA
A De CarliMario Vetrano

Abstract

Our hypothesis was that the Achilles tendon healing process after surgical treatment would be promoted by PRP with a faster return to sports activities. Thirty patients with Achilles tendon rupture and surgically treated with a combined mini-open and percutaneous technique were prospectively enroled in the study. Patients were alternately case-by-case assigned to Group A (control group; 15 patients) or Group B (study group; 15 patients). In Group B, PRP was locally infiltrated both during surgery and 14 days after surgery. Patients in both groups were followed up at 1, 3, 6 and 24 months post-operatively via physical examination, VAS, FAOS and VISA-A scales; ultrasonography (US) and MRI were also conducted at one and 6 months; at the 6-month follow-up, isokinetic and jumping capacity tests were also performed. The VAS, FAOS and VISA-A scale showed no difference between the two groups at 1, 3, 6 and 24 months post-operatively. Isokinetic evaluation showed no differences at both angular speeds. Jumping evaluation showed no difference at 6 months. Also US evaluation showed no differences. MRI data analysis before administration of gadolinium did not reveal significant differences between the two groups. Moreover, after intravenous...Continue Reading

References

Aug 1, 1985·Foot & Ankle·S J Hattrup, K A Johnson
Sep 1, 1993·The American Journal of Sports Medicine·R E FitzGibbonsJ Hill
Jun 25, 1998·Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics·R E MarxK R Georgeff
Oct 2, 2001·British Journal of Sports Medicine·J M RobinsonUNKNOWN Victorian Institute Of Sport Tendon Study Group
Oct 20, 2001·Foot & Ankle International·E M RoosJ Karlsson
Dec 12, 2001·Medicine and Science in Sports and Exercise·C TallonS W Ewen
Jul 20, 2002·The American Journal of Sports Medicine·Jason WongNicola Maffulli
Dec 18, 2002·Comparative Biochemistry and Physiology. Part A, Molecular & Integrative Physiology·Thomas J Koob, Adam P Summers
Apr 17, 2003·Sports Medicine·Timothy MolloyGeorge Murrell
Jan 7, 2005·The Journal of Bone and Joint Surgery. American Volume·Pankaj Sharma, Nicola Maffulli
Mar 23, 2005·Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society·Eduardo AnituaAlan T Nurden
Nov 14, 2006·The American Journal of Sports Medicine·Mikel SánchezIñigo Mujika
Dec 11, 2007·Knee Surgery, Sports Traumatology, Arthroscopy : Official Journal of the ESSKA·A GiganteL de Palma
Nov 6, 2010·The American Journal of Sports Medicine·Thorsten SchepullPer Aspenberg
May 4, 2012·The British Journal of Radiology·R J HodgsonA J Grainger
Aug 14, 2012·Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society·Patrick SadoghiPatrick Vavken
Dec 6, 2012·The American Journal of Sports Medicine·Amy S WasterlainJason L Dragoo
Feb 15, 2013·The American Journal of Sports Medicine·Mario VetranoAndrea Ferretti
Nov 10, 2013·Orthopedics·Riccardo Maria LanzettiAndrea Ferretti

❮ Previous
Next ❯

Citations

Jun 25, 2016·The Journal of Foot and Ankle Surgery : Official Publication of the American College of Foot and Ankle Surgeons·Hakan SarmanCengizhan Kantar
Sep 26, 2016·Knee Surgery, Sports Traumatology, Arthroscopy : Official Journal of the ESSKA·Giuseppe FilardoMaurilio Marcacci
Oct 26, 2018·Current Reviews in Musculoskeletal Medicine·Adrian D K LeJason L Dragoo
Dec 15, 2018·The American Journal of Sports Medicine·Sebastian A MüllerChristopher H Evans
Apr 22, 2018·European Journal of Orthopaedic Surgery & Traumatology : Orthopédie Traumatologie·Giuseppe RolloLuigi Meccariello
Dec 6, 2019·Orthopaedic Journal of Sports Medicine·Jennifer A ZellersKarin Grävare Silbernagel
Sep 28, 2018·Current Reviews in Musculoskeletal Medicine·Peter R Henning, Benjamin J Grear
Oct 22, 2018·Current Reviews in Musculoskeletal Medicine·Kian SetayeshW Stephen Choate
Aug 2, 2017·Health Care Analysis : HCA : Journal of Health Philosophy and Policy·M J McNameeJ Gabe
Jan 21, 2021·International Journal of Molecular Sciences·Sabino PadillaEduardo Anitua
Aug 17, 2021·The Physician and Sportsmedicine·Pauline DaleyAlban Fouasson-Chailloux

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.