Can sociodemographic and clinical variables predict the quality of life of outpatients with major depression?

Psychiatry Research
Marcelo T BerlimMarcelo P Fleck

Abstract

Quality of life (QOL) in depression could be of great value as an outcome measure, especially in determining the effectiveness of treatment strategies. However, for this aim to be accomplished, it is important to clarify the relationship between QOL and a number of potentially mediating factors, such as sociodemographic and clinical variables. For this purpose, we assessed 140 depressed outpatients with the Mini International Neuropsychiatric Interview, the WHOQOL BREF, and the Beck Depression Inventory (BDI). After standard and stepwise multiple regression analyses, the following variables were found to be independent predictors of QOL: BDI score for the physical (adjusted R(2)=0.125) and psychological (adjusted R(2)=0.23) domains, and for the overall QOL estimate (adjusted R(2)=0.226); age, suicidality according to the MINI and BDI score for the social relations domain (adjusted R(2)=0.244); and ethnicity, psychiatric comorbidity, psychotic symptoms and BDI score for the environmental domain (adjusted R(2)=0.328). Limitations of the study include its cross-sectional design, relatively small sample size, and lack of objective measures of depressive symptomatology. Sociodemographic and clinical variables appear to explain less ...Continue Reading

References

Aug 18, 1989·JAMA : the Journal of the American Medical Association·K B WellsJ Ware
Jan 4, 1995·JAMA : the Journal of the American Medical Association·I B Wilson, P D Cleary
Mar 7, 2001·The British Journal of Psychiatry : the Journal of Mental Science·S M Skevington, A Wright
Jun 2, 2001·BMJ : British Medical Journal·A J Carr, I J Higginson
Jan 31, 2003·Psychiatric Services : a Journal of the American Psychiatric Association·Marcelo T BerlimMarcelo P A Fleck
Mar 15, 2003·The Journal of Nervous and Mental Disease·Marcelo T BerlimMarcelo P A Fleck
Feb 6, 2004·General Hospital Psychiatry·George I PapakostasMaurizio Fava
Mar 17, 2004·Social Psychiatry and Psychiatric Epidemiology·Suzanne M SkevingtonMarianne Amir
Apr 17, 2004·Quality of Life Research : an International Journal of Quality of Life Aspects of Treatment, Care and Rehabilitation·S M SkevingtonUNKNOWN WHOQOL Group
Aug 26, 2004·Revista brasileira de psiquiatria : orgão oficial da Associação Brasileira de Psiquiatria, Asociación Psiquiátrica de la América Latina·Marcelo T Berlim, Marcelo P A Fleck
May 17, 2005·Quality of Life Research : an International Journal of Quality of Life Aspects of Treatment, Care and Rehabilitation·Marcelo T BerlimMarcelo P A Fleck
Jun 3, 2005·The American Journal of Psychiatry·Mark Hyman RapaportJean Endicott
Jul 16, 2005·Social Psychiatry and Psychiatric Epidemiology·Fons J TrompenaarsJ De Vries
Jan 18, 2006·Quality of Life Research : an International Journal of Quality of Life Aspects of Treatment, Care and Rehabilitation·Pan Ay-WoanHsiung Ping-Chuan
Jan 18, 2006·Lancet·Klaus P EbmeierJ Douglas Steele

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Citations

Sep 16, 2011·Harvard Review of Psychiatry·Waguih William IsHakMark Hyman Rapaport
May 1, 2012·Quality of Life Research : an International Journal of Quality of Life Aspects of Treatment, Care and Rehabilitation·Waguih William IshakMark Hyman Rapaport
Jul 23, 2013·European Journal of Obstetrics, Gynecology, and Reproductive Biology·Aysun KarabulutNevin Oğuz
Jul 10, 2012·Comprehensive Psychiatry·Marco Antonio Knob CaldieraroMarcelo P Fleck
Jul 17, 2013·Asia-Pacific Psychiatry : Official Journal of the Pacific Rim College of Psychiatrists·Yuping CaoXingguang Luo
Feb 26, 2016·Ciência & saúde coletiva·Flávia Batista PortugalSandra Lúcia Correia Lima Fortes
Apr 21, 2016·Revista brasileira de psiquiatria : orgão oficial da Associação Brasileira de Psiquiatria, Asociación Psiquiátrica de la América Latina·Gabriela L NuernbergNeusa S Rocha
May 7, 2015·Cadernos de saúde pública·Luciana Porto Cavalcante-NóbregaMarcelo Feijó Mello
Dec 1, 2017·Quality of Life Research : an International Journal of Quality of Life Aspects of Treatment, Care and Rehabilitation·Jonna LevolaMauri Aalto
May 24, 2011·Cadernos de saúde pública·Sergio Luís Blay, Marina Sthal Merlin Marchesoni
Mar 15, 2020·Quality of Life Research : an International Journal of Quality of Life Aspects of Treatment, Care and Rehabilitation·Anne BerghöferStephanie Roll

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