Can symptomatology help in the diagnosis of endometriosis? Findings from a national case-control study--Part 1

BJOG : an International Journal of Obstetrics and Gynaecology
Karen BallardJ T Wright

Abstract

To determine the value of patient-reported symptoms in diagnosing endometriosis. A national case-control study. Data from the UK General Practice Research Database for years 1992-2001. A total of 5540 women aged 15-55 years, diagnosed with endometriosis, each matched to four controls without endometriosis. Data were analysed to determine whether specific symptoms were highly indicative of endometriosis. Odds ratios for these symptoms were derived by conditional logistic regression analysis. Symptoms associated with endometriosis. The prevalence of diagnosed endometriosis was 1.5%. A greater proportion of women with endometriosis had abdominopelvic pain, dysmenorrhoea or menorrhagia (73%) compared with controls (20%). Compared with controls, women with endometriosis had increased risks of abdominopelvic pain (OR 5.2 [95% CI: 4.7-5.7]), dysmenorrhoea (OR 8.1 [95% CI: 7.2-9.3]), menorrhagia (OR 4.0 [95% CI: 3.5-4.5]), subfertility (OR 8.2 [95% CI: 6.9-9.9]), dyspareunia and/or postcoital bleeding (OR 6.8 [95% CI: 5.7-8.2]), and ovarian cysts (OR 7.3 [95% CI: 5.7-9.4]), and of being diagnosed with irritable bowel syndrome (IBS) (OR 1.6 [95% CI: 1.3-1.8]) or pelvic inflammatory disease (OR 3.0 [95% CI: 2.5-3.6]). Women with endometr...Continue Reading

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