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Can three-dimensional contacts in protein structures be predicted by analysis of correlated mutations?

Protein Engineering

Mar 1, 1994

I N ShindyalovChris Sander

PMID: 8177884

Abstract

A method has been developed to detect pairs of positions with correlated mutations in protein multiple sequence alignments. The method is based on reconstruction of the phylogenetic tree for a set of sequences and statistical analysis of the distribution of mutations in the branches of ...read more

Mentioned in this Paper

Viral Regulatory and Accessory Proteins
Physicochemical Phenomena
Viral Proteins
Protein Conformation, beta-Strand
Trypure
Mutagenesis Process
Determination, Sequence Homology
Repressor Molecules
DNA Helix Destabilizing Proteins
Ner protein, Enterobacteria phage Mu
98
1
Paper Details
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Can three-dimensional contacts in protein structures be predicted by analysis of correlated mutations?

Protein Engineering

Mar 1, 1994

I N ShindyalovChris Sander

PMID: 8177884

DOI:

Abstract

A method has been developed to detect pairs of positions with correlated mutations in protein multiple sequence alignments. The method is based on reconstruction of the phylogenetic tree for a set of sequences and statistical analysis of the distribution of mutations in the branches of ...read more

Mentioned in this Paper

Viral Regulatory and Accessory Proteins
Physicochemical Phenomena
Viral Proteins
Protein Conformation, beta-Strand
Trypure
Mutagenesis Process
Determination, Sequence Homology
Repressor Molecules
DNA Helix Destabilizing Proteins
Ner protein, Enterobacteria phage Mu
98
1
Paper Details
References
  • References
  • Citations131
  • finger pointing at paper

    References currently unavailable

    We're still populating references for this paper, please check back later.
  • References
  • Citations131
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