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Can three-dimensional contacts in protein structures be predicted by analysis of correlated mutations?

Protein Engineering

Mar 1, 1994

Ilya N ShindyalovChris Sander

PMID: 8177884

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Abstract

A method has been developed to detect pairs of positions with correlated mutations in protein multiple sequence alignments. The method is based on reconstruction of the phylogenetic tree for a set of sequences and statistical analysis of the distribution of mutations in the branches of ...read more

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  • Can three-dimensional contacts in protein structures be predicted by analysis of correlated mutations?

    Protein Engineering

    Mar 1, 1994

    Ilya N ShindyalovChris Sander

    PMID: 8177884

    DOI:

    Abstract

    A method has been developed to detect pairs of positions with correlated mutations in protein multiple sequence alignments. The method is based on reconstruction of the phylogenetic tree for a set of sequences and statistical analysis of the distribution of mutations in the branches of ...read more

    93
    1
    Paper Details
    References
    • References
    • Citations124

      References currently unavailable

      We're still populating references for this paper, please check back later.
    • References
    • Citations124
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