Can utility-weighted health-related quality-of-life estimates capture health effects of quality improvement for depression?

Medical Care
C Donald SherbourneK B Wells

Abstract

Utility methods that are responsive to changes in desirable outcomes are needed for cost-effectiveness (CE) analyses and to help in decisions about resource allocation. Evaluated is the responsiveness of different methods that assign utility weights to subsets of SF-36 items to average improvements in health resulting from quality improvement (QI) interventions for depression. A group level, randomized, control trial in 46 primary care clinics in six managed care organizations. Clinics were randomized to one of two QI interventions or usual care. One thousand one hundred thirty-six patients with current depressive symptoms and either 12-month, lifetime, or no depressive disorder identified through screening 27,332 consecutive patients. Utility weighted SF-12 or SF-36 measures, probable depression, and physical and mental health-related quality of life scores. Several utility-weighted measures showed increases in utility values for patients in one of the interventions, relative to usual care, that paralleled the improved health effects for depression and emotional well being. However, QALY gains were small. Directly elicited utility values showed a paradoxical result of lower utility during the first year of the study for interv...Continue Reading

References

Jan 1, 1989·Journal of Clinical Epidemiology·D G Froberg, R L Kane
Jan 1, 1989·Journal of Clinical Epidemiology·D G Froberg, R L Kane
Dec 1, 1993·Quality of Life Research : an International Journal of Quality of Life Aspects of Treatment, Care and Rehabilitation·D A Revicki, R M Kaplan
Jul 1, 1996·Medical Decision Making : an International Journal of the Society for Medical Decision Making·J L Bosch, M G Hunink
Oct 23, 1996·JAMA : the Journal of the American Medical Association·J E SiegelM R Gold
Jan 1, 1997·Medical Decision Making : an International Journal of the Society for Medical Decision Making·D G FrybackB E Klein
Nov 17, 1998·Journal of Clinical Epidemiology·J BrazierK Thomas
Jan 30, 1999·Health Psychology : Official Journal of the Division of Health Psychology, American Psychological Association·P NormanR Bell
May 8, 1995·PharmacoEconomics·D FeenyG W Torrance
May 8, 1995·PharmacoEconomics·G W TorranceM Boyle
May 7, 1999·Medical Decision Making : an International Journal of the Society for Medical Decision Making·A Shmueli
May 7, 1999·Medical Decision Making : an International Journal of the Society for Medical Decision Making·L LundbergL Borgquist
Feb 9, 1986·Journal of Health Economics·G W Torrance
May 21, 1999·Medical Care·L A LenertC E Schwartz
Jun 3, 1999·Journal of General Internal Medicine·C D SherbourneK B Wells
Sep 25, 1999·Health Affairs·L V RubensteinK B Wells
Oct 28, 1999·Journal of Health Services Research & Policy·J BrazierC Green
Jan 14, 2000·JAMA : the Journal of the American Medical Association·K B WellsL V Rubenstein
Jan 19, 2000·Medical Decision Making : an International Journal of the Society for Medical Decision Making·S J JansenJ Kievit
Jul 20, 2000·Medical Care·L A LenertK B Wells
Sep 6, 2000·Psychiatric Services : a Journal of the American Psychiatric Association·K J BennettR Guscott

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Citations

Apr 13, 2011·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·C M McDonoughA N A Tosteson
Oct 12, 2011·Quality of Life Research : an International Journal of Quality of Life Aspects of Treatment, Care and Rehabilitation·Dennis W RaischWalter Ling
Mar 7, 2012·Quality of Life Research : an International Journal of Quality of Life Aspects of Treatment, Care and Rehabilitation·Mangala RajanAnushua Sinha
Jun 25, 2009·Journal of Orthopaedic Trauma·Dianne M BryantGeorge Yves Laflamme
Nov 26, 2010·Medical Decision Making : an International Journal of the Society for Medical Decision Making·Christine M McDonoughJames N Weinstein
Jul 28, 2013·Health and Quality of Life Outcomes·Katerina PapageorgiouAdelita V Ranchor
Jan 26, 2007·PharmacoEconomics·Christine M McDonough, Anna N A Tosteson
Jul 31, 2009·PharmacoEconomics·Ling-Hsiang Chuang, Paul Kind
Jan 3, 2012·The Spine Journal : Official Journal of the North American Spine Society·Shawn S Richardson, Sigurd Berven
Jun 7, 2005·European Psychiatry : the Journal of the Association of European Psychiatrists·Dag IsacsonLars von Knorring
Dec 1, 2002·Expert Review of Pharmacoeconomics & Outcomes Research·Todd A Lee, Kevin B Weiss
Sep 13, 2005·Health and Quality of Life Outcomes·Leslie A LenertChristine Elnitsky
Apr 4, 2014·Medical Decision Making : an International Journal of the Society for Medical Decision Making·Syed Mohiuddin, Katherine Payne
Aug 21, 2003·Medical Decision Making : an International Journal of the Society for Medical Decision Making·Todd A LeeSean D Sullivan
Feb 12, 2008·Medical Decision Making : an International Journal of the Society for Medical Decision Making·Duncan Mortimer, Leonie Segal
Aug 30, 2008·Medical Decision Making : an International Journal of the Society for Medical Decision Making·Maria Orlando EdelenGary Rachelefsky
Feb 4, 2012·Medical Decision Making : an International Journal of the Society for Medical Decision Making·Paul Dolan, Robert Metcalfe
Aug 21, 2004·Medical Care·Nishan SenguptaDenise Globe
Oct 3, 2006·The British Journal of Psychiatry : the Journal of Mental Science·Simon GilbodyPaula Whitty
Oct 19, 2012·The Cochrane Database of Systematic Reviews·Janine ArcherPeter Coventry
Nov 18, 2017·Quality of Life Research : an International Journal of Quality of Life Aspects of Treatment, Care and Rehabilitation·John F DickersonFrances L Lynch
Dec 2, 2005·The British Journal of Psychiatry : the Journal of Mental Science·Robert RosenheckJeffrey Lieberman
Jun 5, 2016·Medical Care·Frances L LynchAlex L MacMillan

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