Can visuospatial measures improve the diagnosis of Alzheimer's disease?

Alzheimer's & Dementia : Diagnosis, Assessment & Disease Monitoring
Shirin SalimiJames R Burrell

Abstract

Overlapping and evolving symptoms lead to ambiguity in the diagnosis of dementia. Visuospatial function relies on parietal lobe function, which may be affected in the early stages of Alzheimer's disease (AD). This review evaluates visuospatial dysfunction in patients with AD, frontotemporal dementia, dementia with Lewy bodies, and vascular dementia to determine the diagnostic and prognostic potential of visuospatial tasks in AD. A systematic search of studies (1960-2016) investigating visuospatial dysfunction in dementia was conducted. Tests measuring construction, specifically Block Design and Clock Drawing Test, and visual memory, specifically Rey-Osterrieth Complex Figure recall and topographical tasks, show the greatest diagnostic potential in dementia. The Benton visual retention, Doors and People, and topographical memory tests show potential as prognostic markers. Tests of visuospatial function demonstrate significant diagnostic and prognostic potential in dementia. Further studies with larger samples of pathologically confirmed cases are required to verify clinical utility.

References

Jan 1, 1991·Annals of Neurology·A Cronin-GolombK S Banks
Mar 1, 1990·Neurology·M F MendezP J Whitehouse
Jul 1, 1996·Brain and Cognition·D GalaskoL Hansen
Mar 1, 1997·Journal of Neurology, Neurosurgery, and Psychiatry·K K GnanalinghamP Bannister
Nov 1, 1996·Journal of the International Neuropsychological Society : JINS·N A PachanaN Berman
Oct 20, 1998·Journal of Clinical and Experimental Neuropsychology·L J RapportP J Bonello
Dec 29, 1998·Archives of Neurology·T ShimomuraT Hanihara
Mar 16, 2000·Alzheimer Disease and Associated Disorders·R J Perry, J R Hodges
Jun 22, 2000·International Journal of Geriatric Psychiatry·K I Shulman
Jun 30, 2001·European Journal of Neurology : the Official Journal of the European Federation of Neurological Societies·S SiriS F Cappa
Sep 14, 2001·Psychiatry and Clinical Neurosciences·Y KitabayashiK Fukui
Feb 15, 2002·Journal of the International Neuropsychological Society : JINS·Kylie S FowlerWilliam J Louis
May 8, 2002·International Journal of Geriatric Psychiatry·Rita MorettiAntonio Bava
May 27, 2003·International Journal of Geriatric Psychiatry·Martine SimardDavid Myran
Jun 12, 2003·Cognitive and Behavioral Neurology : Official Journal of the Society for Behavioral and Cognitive Neurology·Deborah A Cahn-WeinerRobert A Stern
Sep 6, 2003·Frontiers in Bioscience : a Journal and Virtual Library·David S Geldmacher
Oct 1, 1962·Archives of Neurology·A L BENTON, M L FOGEL
Sep 27, 2003·The European Journal of Neuroscience·Andy C H LeeKim S Graham
Oct 16, 2003·Dementia and Geriatric Cognitive Disorders·Andrew D BlackwellJohn R Hodges
Oct 1, 1993·Archives of Clinical Neuropsychology : the Official Journal of the National Academy of Neuropsychologists·D J LibonL P Sands
Dec 10, 2003·Neurology·Anthony M MonacelliCharles J Duffy
Dec 11, 2003·Cognitive and Behavioral Neurology : Official Journal of the Society for Behavioral and Cognitive Neurology·Joel H KramerBruce L Miller
Mar 3, 2004·Annals of Neurology·Maria Luisa Gorno-TempiniBruce L Miller
Apr 15, 2004·Journal of Neurology·Hidekazu TomimotoHiroshi Shibasaki
Aug 25, 2004·Journal of Internal Medicine·M J de LeonH Rusinek
Dec 4, 2004·International Journal of Geriatric Psychiatry·Henry O'ConnellBrian A Lawlor
Aug 27, 2005·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Randy L BucknerMark A Mintun
Oct 26, 2005·Neurology·David K JohnsonJames E Galvin
Dec 6, 2005·Neuropsychology Review·Michal Harciarek, Krzysztof Jodzio
Jan 13, 2006·Brain : a Journal of Neurology·Pietro TiraboschiJody Corey-Bloom
Apr 1, 2006·Journal of the International Neuropsychological Society : JINS·Mervin BlairNikoletta Bodi
May 31, 2006·Dementia and Geriatric Cognitive Disorders·Stefania CastiglioniMassimo Franceschi
Feb 10, 2007·Progress in Neuro-psychopharmacology & Biological Psychiatry·Anikó EgerháziIstván Degrell
Feb 20, 2007·Archives of Clinical Neuropsychology : the Official Journal of the National Academy of Neuropsychologists·Robert H PietrzakPeter J Snyder
Mar 21, 2007·Journal of Neurology, Neurosurgery, and Psychiatry·A D Hutchinson, J L Mathias
Jul 12, 2008·Annual Review of Psychology·David P Salmon, Mark W Bondi
Nov 18, 2008·Alzheimer's & Dementia : the Journal of the Alzheimer's Association·Katherine WildJeffrey Kaye

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Citations

Nov 7, 2019·Archives of Clinical Neuropsychology : the Official Journal of the National Academy of Neuropsychologists·Rafaela Martins-RodriguesBernardino Fernández-Calvo
Oct 30, 2020·Journal of Clinical Medicine·Cosimo TuenaElisa Pedroli
Aug 9, 2020·Journal of the International Neuropsychological Society : JINS·Yamile BocanegraYakeel T Quiroz
Feb 24, 2021·Trends in Cognitive Sciences·Federica Conti, Muireann Irish
Oct 1, 2020·Cortex; a Journal Devoted to the Study of the Nervous System and Behavior·David FoxeOlivier Piguet
May 11, 2021·Journal of Alzheimer's Disease : JAD·Matthew B HunterGraciela Muniz-Terrera
Jul 3, 2021·Healthcare·Areej Y BayahyaSultan H AlAmri
Jul 6, 2021·Brain Communications·Flavia LoretoParesh A Malhotra
Jul 8, 2021·Arquivos de neuro-psiquiatria·Stefan Frisch, Alexandre Métraux
Jul 27, 2021·European Journal of Neurology : the Official Journal of the European Federation of Neurological Societies·David FoxeOlivier Piguet

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