Can we influence the epidemiology of dementia? Perspectives from population-based studies

Postgraduate Medical Journal
Ratika BirdiDaniel Davis

Abstract

The worldwide prevalence of dementia is predicted to rise significantly in the next three decades. However, these projections have not taken into account the role of modifiable risk factors and whether any prevention strategies might influence the predicted trend. Attempts at pharmacological disease modification have largely been disappointing, and the difficulties in conducting dementia trials are reviewed here. In contrast, recent population studies in high-income countries suggest that the epidemiology may be changing with a possible decline in incident dementia, or even a reduction in age-specific prevalence. Therefore, efforts to develop public health interventions may prove to be the more successful approach to addressing dementia at a societal level.

References

Sep 1, 1988·The British Journal of Psychiatry : the Journal of Mental Science·B J Mowry, P W Burvill
Apr 6, 1999·Archives of Neurology·R C PetersenE Kokmen
Jul 22, 2005·Lancet Neurology·Chengxuan QiuLaura Fratiglioni
Aug 2, 2006·Journal of Geriatric Psychiatry and Neurology·John C S Breitner
Sep 7, 2007·Acta Psychiatrica Scandinavica·A LoboUNKNOWN ZARADEMP Workgroup
Mar 11, 2009·Archives of Neurology·Annette L FitzpatrickJosé A Luchsinger
Sep 23, 2010·Vascular Health and Risk Management·Suzanne A LigthartEdo Richard
Jul 1, 2009·Therapeutic Advances in Neurological Disorders·Sean P KennellyRose Anne Kenny
Jul 22, 2011·Lancet Neurology·Deborah E Barnes, Kristine Yaffe
Jan 24, 2012·Alzheimer's & Dementia : the Journal of the Alzheimer's Association·Bradley T HymanThomas J Montine
Oct 23, 2012·Lancet·Carol Brayne, Daniel Davis
Nov 20, 2012·Archives of Medical Research·Ana Luisa Sosa-OrtizMartin J Prince
Jan 12, 2013·Alzheimer's & Dementia : the Journal of the Alzheimer's Association·Martin PrinceCleusa P Ferri
May 7, 2013·The Medical Clinics of North America·Jeffrey L CummingsPhilip Scheltens
Jan 11, 2014·Nature Biotechnology·Michael HayJesse Rosenthal
May 7, 2014·Journal of Alzheimer's Disease : JAD·Luigi Yuri Di MarcoAlejandro F Frangi
Jul 16, 2014·Alzheimer's Research & Therapy·Jeffrey L CummingsKate Zhong

❮ Previous
Next ❯

Citations

Mar 22, 2019·The British Journal of Psychiatry : the Journal of Mental Science·Kamaldeep Bhui
Jun 13, 2020·Journal of Clinical Medicine·Javier SantabárbaraPatricia Gracia-García
Jun 24, 2020·Alzheimer's & Dementia : the Journal of the Alzheimer's Association·Blossom C M StephanCarol Brayne
Jun 12, 2019·Aging & Mental Health·Kirsten Nabe-NielsenRudi G J Westendorp
Aug 7, 2020·Age and Ageing·Blossom Christa Maree Stephan, Mario Siervo
Oct 24, 2018·Journal of Alzheimer's Disease : JAD·Blossom C M StephanLouise Robinson
Oct 5, 2020·Journal of the American Medical Directors Association·Ana Rita SilvaJoaquim Cerejeira
Aug 15, 2021·Journal of Aging and Health·Andreas M AppelKirsten Nabe-Nielsen

❮ Previous
Next ❯

Related Concepts

Related Feeds

Epidemiology of Aging

This feed focuses on epidemiology of aging and aging-related conditions, including Alzheimer’s disease, dementia, and age-associated cognitive impairment. Here is the latest research.