Canadian Public Health Laboratory Network position statement: Non-culture based diagnostics for gastroenteritis and implications for public health investigations

Canada Communicable Disease Report = Relevé Des Maladies Transmissibles Au Canada
B BerengerCanadian Public Health Laboratory Network

Abstract

As clinical laboratories transition to using culture-independent detection test (CIDT) panels for cases of acute gastroenteritis, culture of clinical specimens is becoming less common. The reduction in bacterial cultures available for public health activities is expected to hinder surveillance and outbreak response by public health laboratories at the local, provincial, national and international levels. These recommendations are intended to serve as guidelines for the implementation of CIDT panels in frontline laboratories in Canada. The United States of America has already seen a significant reduction in culture of stool specimens despite the Association of Public Health Laboratories recommendation to perform reflex culture on positive CIDT specimens. Priority public health organisms addressed in these Canadian guidelines include Shiga toxin-producing Escherichia coli, Shigella and Salmonella and, under regional circumstances, other organisms such as Campylobacter jejuni/coli and Yersinia enterocolitica. These recommendations suggest active engagement between primary diagnostic laboratories and provincial public health laboratories to determine the workflow and protocols for reflex or parallel culture. Consequently, notifiabl...Continue Reading

References

Oct 1, 1983·Journal of Clinical Microbiology·W L WangM J Blaser
Apr 1, 1981·Journal of Clinical Microbiology·J G Wells, G K Morris
Apr 24, 2014·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Faisal AlasmariErik R Dubberke
Nov 5, 2015·Canada Communicable Disease Report = Relevé Des Maladies Transmissibles Au Canada·P BélangerM Phypers

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Citations

Aug 4, 2019·Diagnostic Microbiology and Infectious Disease·Byron Michael BerengerLinda Chui

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