Canadian Rheumatology Association Recommendations for the Assessment and Monitoring of Systemic Lupus Erythematosus

The Journal of Rheumatology
Stephanie O KeelingNancy Santesso

Abstract

To develop recommendations for the assessment of people with systemic lupus erythematosus (SLE) in Canada. Recommendations were developed using the GRADE (Grading of Recommendations Assessment, Development, and Evaluation) approach. The Canadian SLE Working Group (panel of Canadian rheumatologists and a patient representative from Canadian Arthritis Patient Alliance) was created. Questions for recommendation development were identified based on the results of a previous survey of SLE practice patterns of members of the Canadian Rheumatology Association. Systematic literature reviews of randomized trials and observational studies were conducted. Evidence to Decision tables were prepared and presented to the panel at 2 face-to-face meetings and online. There are 15 recommendations for assessing and monitoring SLE, with varying applicability to adult and pediatric patients. Three recommendations focus on diagnosis, disease activity, and damage assessment, suggesting the use of a validated disease activity score per visit and annual damage score. Strong recommendations were made for cardiovascular risk assessment and measuring anti-Ro and anti-La antibodies in the peripartum period and conditional recommendations for osteoporosis a...Continue Reading

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Citations

Aug 14, 2019·Current Opinion in Rheumatology·Alexandra LadouceurSasha Bernatsky
Feb 3, 2019·The Journal of Rheumatology·Murray B UrowitzDafna D Gladman
Jun 2, 2020·Expert Review of Clinical Immunology·Megan R W Barber, Ann E Clarke
Sep 29, 2020·Journal of Clinical Epidemiology·Nancy SantessoGordon Guyatt
Apr 18, 2021·Calcified Tissue International·Claudia Mendoza-PintoSocorro Méndez-Martínez
May 12, 2021·International Journal of Rheumatic Diseases·Amelia SantosaManjari Lahiri
Mar 4, 2021·Journal of Clinical Rheumatology : Practical Reports on Rheumatic & Musculoskeletal Diseases·Dylan HardenberghHoma Timlin

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