Canal surgery in adult glaucomas

Current Opinion in Ophthalmology
David G GodfreyArvind Neelakantan


Outflow procedures for glaucoma surgery have remained popular in the last decade, including trabeculectomy, glaucoma drainage devices, and deep sclerectomy/viscocanalostomy. In the last few years, the surgical armamentarium for glaucoma has vastly increased. Surgeons are using more procedures aimed at creating bleb-free surgery. Schlemm's canal surgery is experiencing a renaissance. This article concentrates on three of the more commonly performed canal procedures: trabeculotomy ab interno (Trabectome), Canaloplasty, and trabeculotomy ab externo. Trabeculotomy ab interno performed with the Trabectome has been shown to lower intraocular pressure (IOP) almost 40% by 12 months with minimal complications. Trabectome alone, as well as combined with cataract surgery, appears to lower IOP quite well. Canaloplasty has also been shown to lower IOP by 38% and combined with cataract surgery, IOP was lowered 44% at 24 months. Trabeculotomy lowers IOP well, especially in older adults. Phacotrabeculotomy lowers IOP to 21 mmHg or less in 84% of patients with supplemental use of medications, and in 36% of patients without at 3 years. Canal surgery has proven to be an alternative to traditional glaucoma surgery, lowering IOP relatively well. Su...Continue Reading


Sep 1, 1995·Archives of Ophthalmology·A D Beck, M G Lynch
Aug 22, 2000·Journal of AAPOS : the Official Publication of the American Association for Pediatric Ophthalmology and Strabismus·M E MendicinoM J Lynn
Sep 18, 2001·Journal of Glaucoma·Masaki TanitoEtsuo Chihara
Oct 19, 2002·The British Journal of Ophthalmology·D Spiegel, K Kobuch
Oct 12, 2004·Journal of Cataract and Refractive Surgery·Ilgaz Sagdic YalvacSunay Duman
May 11, 2005·Ophthalmology·Don MincklerBrian A Francis
Jul 26, 2005·American Journal of Ophthalmology·Ahmed M Abdelrahman
Sep 22, 2006·Journal of Glaucoma·Jianbo Zhou, Gregory T Smedley
Sep 22, 2006·Journal of Glaucoma·Masami ParkEtsuo Chihara
Oct 24, 2006·American Journal of Ophthalmology·Steven J GeddeJoyce C Schiffman
Nov 7, 2006·American Journal of Ophthalmology·Steven J GeddeDonald L Budenz
May 29, 2007·Advances in Therapy·Detlev SpiegelRichard A Hill
Jun 26, 2007·Journal of Cataract and Refractive Surgery·George J C JinJason J Jones
Feb 28, 2008·Current Opinion in Ophthalmology·Theodoros Filippopoulos, Douglas J Rhee
Jun 24, 2008·Journal of Cataract and Refractive Surgery·Brian A FrancisTrabectome Study Group


Dec 18, 2010·Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft·M MatthaeiM Klemm
Jul 3, 2010·Clinical Ophthalmology·George KitsosKonstantinos Psilas
Feb 16, 2013·Indian Journal of Ophthalmology·Sundaram Natarajan
Dec 22, 2010·Indian Journal of Ophthalmology·R Ramakrishnan, Mona Khurana
Feb 10, 2010·Middle East African Journal of Ophthalmology·Mahmoud A Khaimi
Jul 7, 2011·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Holger BullManfred Tetz
Dec 6, 2011·Survey of Ophthalmology·M Reza RazeghinejadGeorge L Spaeth
Feb 26, 2015·Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft·J Matlach, T Klink
Oct 1, 2011·Saudi Journal of Ophthalmology : Official Journal of the Saudi Ophthalmological Society·Ben J Harvey, Mahmoud A Khaimi
Mar 1, 2016·Japanese Journal of Ophthalmology·Nobuyuki ShojiKimiya Shimizu
May 31, 2016·Journal of Ophthalmology·Carlo CaginiStefano Lippera
Jul 15, 2015·The Cochrane Database of Systematic Reviews·Mingjuan Lisa ZhangHenry Jampel
Jan 4, 2013·Journal of Glaucoma·Ronald L Fellman, Davinder S Grover
Nov 6, 2018·Journal of Glaucoma·Masayuki KasaharaKazuhiro Matsumura
Dec 7, 2010·Optometry and Vision Science : Official Publication of the American Academy of Optometry·M Reza Razeghinejad, George L Spaeth
Oct 17, 2014·Journal of Glaucoma·Paolo BrusiniClaudia Tosoni
Jan 18, 2012·Current Opinion in Ophthalmology·Davinder S Grover, Oluwatosin Smith
Jun 3, 2015·International Ophthalmology Clinics·Mohamed S Sayed, Richard K Lee
Feb 25, 2020·European Journal of Ophthalmology·Mehmet Ozgur Cubuk, Erkan Unsal
Jun 9, 2020·Ophthalmic Surgery, Lasers & Imaging Retina·Daniel M Vu, Anna K Junk
Oct 1, 2011·Saudi Journal of Ophthalmology : Official Journal of the Saudi Ophthalmological Society·Tarek M Eid
Feb 5, 2015·Journal of Glaucoma·Ibrahim Feyzi HepsenGaye Dişli
Aug 10, 2020·Journal of Glaucoma·Duygu YalinbasIbrahim Feyzi Hepsen

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