Cancer associates with risk and severe events of COVID-19: A systematic review and meta-analysis

International Journal of Cancer. Journal International Du Cancer
Yehong TianFengyu Zhang

Abstract

Evidence is mounting to indicate that cancer patients may have more likelihood of having coronavirus disease 2019 (COVID-19) but lack consistency. A robust estimate is urgently needed to convey appropriate information to the society and the public, in the time of ongoing COVID-19 pandemic. We performed a systematic review and meta-analysis through a comprehensive literature search in major databases in English and Chinese, and two investigators conducted publication selection and data extraction independently. A meta-analysis was used to obtain estimates of pooled prevalence of cancer in patients with COVID-19 and determine the association of cancer with severe events, after assessment of potential heterogeneity, publication bias, and correction for the estimates when necessary. Total 38 studies comprising 7,094 patients with COVID-9 were included; the pooled prevalence of cancer was estimated at 2.3% (95% confidence limit[CL] [0.018, 0.029]; p<0.001) overall and 3.2% (95% CL [0.023,0.041]; p<0.001) in Hubei province; the corresponding estimates were 1.4% and 1.9% after correction for publication bias; cancer was significantly associated with the events of severe cases (odds ratio [OR]=2.20, 95% CL[1.53, 3.17]; p<0.001) and dea...Continue Reading

References

Jul 12, 2002·Statistics in Medicine·Julian P T Higgins, Simon G Thompson
Jul 23, 2009·BMJ : British Medical Journal·David MoherUNKNOWN PRISMA Group
Jan 30, 2013·Chinese Journal of Cancer Research = Chung-kuo Yen Cheng Yen Chiu·Wan-Qing ChenJie He
Oct 26, 2013·Nature Reviews. Immunology·Albert C ShawRuth R Montgomery
Aug 2, 2016·Chinese Journal of Cancer Research = Chung-kuo Yen Cheng Yen Chiu·Shuzheng LiuChengzeng Wang
Sep 20, 2018·Cardiovascular Diabetology·Cheng LiuTutiguli Maimaiti
Sep 30, 2018·Travel Medicine and Infectious Disease·Hui ZhangJiakui Li
Dec 14, 2018·Hypertension Research : Official Journal of the Japanese Society of Hypertension·Yi LuoAbudurexiti Zeyaweiding
Jan 30, 2020·The New England Journal of Medicine·Qun LiZijian Feng
Feb 8, 2020·JAMA : the Journal of the American Medical Association·Dawei WangZhiyong Peng
Feb 19, 2020·The Lancet Oncology·Wenhua LiangJianxing He
Feb 23, 2020·The Lancet. Respiratory Medicine·Zhe XuFu-Sheng Wang
Feb 28, 2020·The Lancet Infectious Diseases·Heshui ShiChuansheng Zheng
Feb 29, 2020·European Journal of Nuclear Medicine and Molecular Imaging·Xi XuJinxin Liu
Feb 29, 2020·The New England Journal of Medicine·Wei-Jie GuanUNKNOWN China Medical Treatment Expert Group for Covid-19
Feb 29, 2020·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Jian WuLanjuan Li
Mar 7, 2020·The Lancet Oncology·Yang XiaHuahao Shen
Mar 17, 2020·The Journal of Infection·Jun ChenHongzhou Lu
Mar 17, 2020·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Pingzheng MoYongxi Zhang
Mar 17, 2020·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Zhongliang WangRuiguang Zhang
Mar 22, 2020·Journal of Medical Virology·Suxin WanRuishan Yang
Mar 29, 2020·The European Respiratory Journal·Wei-Jie GuanUNKNOWN China Medical Treatment Expert Group for Covid-19
Apr 3, 2020·Expert Review of Clinical Immunology·Amene Saghazadeh, Nima Rezaei
Apr 3, 2020·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Jianlei CaoQiang Liu
Apr 7, 2020·JCO Global Oncology·Aakash DesaiRupak Desai
Apr 8, 2020·Annals of the American Thoracic Society·Rong-Hui DuHuan-Zhong Shi
Apr 11, 2020·American Journal of Respiratory and Critical Care Medicine·Yun FengJieming Qu
Apr 14, 2020·Psycho-oncology·Maggie WatsonRichard Fielding
Apr 15, 2020·International Journal of Infectious Diseases : IJID : Official Publication of the International Society for Infectious Diseases·Ruirui WangLeilei Shen
Apr 16, 2020·The Journal of Allergy and Clinical Immunology·Xiaochen LiJianping Zhao

❮ Previous
Next ❯

Citations

Oct 3, 2020·International Journal of Cancer. Journal International Du Cancer·Jennet Williams, Justin Stebbing
Feb 16, 2021·Frontiers in Pharmacology·Keiichi TominagaAtsushi Irisawa
Mar 30, 2021·Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer·Livia Costa de OliveiraSimone Garruth Dos Santos Machado Sampaio
Apr 14, 2021·BMC Public Health·Sanaz SohrabizadehMohammad Hossein Vaziri
Apr 30, 2021·Frontiers in Molecular Biosciences·Vivek R Bora, Bhoomika M Patel
May 4, 2021·Quality of Life Research : an International Journal of Quality of Life Aspects of Treatment, Care and Rehabilitation·Gözde ÖnalMeral Huri
Apr 15, 2021·Oral Diseases·Leticia Rodrigues-OliveiraAna Carolina Prado-Ribeiro
May 6, 2021·Journal of Primary Care & Community Health·Frances R GreathouseBeth A Bailey
Jul 2, 2021·Frontiers in Psychology·Emily C SorianoJean-Philippe Laurenceau
Aug 6, 2021·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·Henri-Corto StoekléPhilippe Beuzeboc
Sep 10, 2021·The Oncologist·Oscar ArrietaRenata Baéz-Saldaña
Oct 29, 2021·Integrative Cancer Therapies·Sarah FolsomGabriel Lopez
Oct 29, 2021·Frontiers in Oncology·Manuel ZorziMassimo Rugge

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.