journal cover

Cancer immunoediting: from immunosurveillance to tumor escape

Nature Immunology

Oct 31, 2002

Gavin P DunnRobert D Schreiber

Download from

Publisher
PubMed

Abstract

The concept that the immune system can recognize and destroy nascent transformed cells was originally embodied in the cancer immunosurveillance hypothesis of Burnet and Thomas. This hypothesis was abandoned shortly afterwards because of the absence of strong experimental evidence suppor...read more

Mentioned in this Paper

Immune System
Tumor Escape
Transplantation Immunology
Neoplasms
Sanguisorba
Immunocompromised Host
Thomas Syndrome
Therapeutic Immunosuppression
Mice, Nude
Mice, Knockout
3
3
2090
1
Paper Details
References
  • References78
  • Citations1360
12345...
  • References78
  • Citations1360
12345...

Feeds With Similar Papers

Tumor Evasion of the Immune System

Tumor evasion of the immune system includes cells that operate their own growth and develop various strategies to escape from immune surveillance. Discover the latest research on tumor evasion of the immune system here.

Human Immune Variation: Genetics, Gender & Time

Establishing the normal range of phenotypic variation within and between individuals requires consideration of contributions from genetics and the environment. Find the latest research on variations in the human immune system here.

Immunosuppression

Immunosuppression trends for solid organ transplantation have undergone a perceptible shift over the past decade. Discover the latest research on immunosuppression here.

Immune System in Humans: Tissues & Ages

Mapping the human immune system spatially, within and between tissues, will provide the basis for studying mechanisms of tissue residency and the effects of aging. Find new research on analysis of the immune system by multiple approaches here.

Immune Tolerance

Immune tolerance happens when the immune system is not responsive to a substance or organism and does not elicit an immune response. This is a normal physiological response for some antigens, especially when detecting self from non-self. This has been a potential area of therapy for some disorders. Here is the latest research on immune tolerance.

Human Immune Variation: Genetic, Gender & Time

Establishing the normal range of phenotypic variation within and between individuals requires consideration of contributions from genetics and the environment. Find the latest research on variations in the human immune system here.

Immunologic Surveillance

Immunological surveillance occurs when T-cells detect and destroy virally infected or neoplastically transformed cells in the body. Discover the latest research on immunologic surveillance here.

Related Papers

Annual Review of Immunology

The three Es of cancer immunoediting

Annual Review of ImmunologyMarch 23, 2004
Gavin P DunnRobert D Schreiber
© 2020 Meta ULC. All rights reserved

Cancer immunoediting: from immunosurveillance to tumor escape

Nature Immunology

Oct 31, 2002

Gavin P DunnRobert D Schreiber

PMID: 12407406

DOI: 10.1038/ni1102-991

Abstract

The concept that the immune system can recognize and destroy nascent transformed cells was originally embodied in the cancer immunosurveillance hypothesis of Burnet and Thomas. This hypothesis was abandoned shortly afterwards because of the absence of strong experimental evidence suppor...read more

Mentioned in this Paper

Immune System
Tumor Escape
Transplantation Immunology
Neoplasms
Sanguisorba
Immunocompromised Host
Thomas Syndrome
Therapeutic Immunosuppression
Mice, Nude
Mice, Knockout
3
3
2090
1

Feeds With Similar Papers

Tumor Evasion of the Immune System

Tumor evasion of the immune system includes cells that operate their own growth and develop various strategies to escape from immune surveillance. Discover the latest research on tumor evasion of the immune system here.

Human Immune Variation: Genetics, Gender & Time

Establishing the normal range of phenotypic variation within and between individuals requires consideration of contributions from genetics and the environment. Find the latest research on variations in the human immune system here.

Related Papers

Annual Review of Immunology

The three Es of cancer immunoediting

Annual Review of ImmunologyMarch 23, 2004
Gavin P DunnRobert D Schreiber
Paper Details
References
  • References78
  • Citations1360
12345...
  • References78
  • Citations1360
12345...

Download from

Publisher
PubMed
/papers/cancer-immunoediting-from-immunosurveillance-to/12407406