Cancer immunotherapy by fusions of dendritic cells and tumor cells

Immunotherapy
Shigeo KoidoHisao Tajiri

Abstract

Dendritic cells (DCs) are potent professional antigen-presenting cells and play a critical role in the induction of primary immune responses. DC-based vaccination represents a potentially powerful strategy for cancer immunotherapy. Thus, the use of cancer vaccines to eliminate residual tumor cells is a promising area of investigation. The immunotherapy of tumor antigen-loaded DCs has now been demonstrated in cancer patients and some clinical responses without any significant toxicity. Fusions of DCs and tumor cells represent an alternative but promising approach to overcome the inability of tumor antigens to induce a sustainable T-cell response. This review deals with recent progress in the immunotherapy of cancer with fusions of DCs and tumor cells.

References

Jan 1, 1991·Annual Review of Immunology·R M Steinman
Jan 1, 1988·Annual Review of Genetics·S Lindquist, E A Craig
Jan 1, 1993·Annual Review of Cell Biology·C Georgopoulos, W J Welch
Dec 20, 1995·Biochimica Et Biophysica Acta·S PattonA P Spicer
Jan 1, 1996·The Journal of Experimental Medicine·C M CelluzziL D Falo
Jan 1, 1996·The Journal of Experimental Medicine·J W Young, K Inaba
Apr 1, 1998·Nature·J Banchereau, R M Steinman
Apr 16, 1998·International Journal of Cancer. Journal International Du Cancer·L LespagnardM Moser
May 30, 1998·Proceedings of the National Academy of Sciences of the United States of America·J GongD Kufe
Mar 2, 1999·The Journal of Experimental Medicine·R E ToesC J Melief
Apr 9, 1999·Science·E OstromD Policansky
Feb 26, 2000·Proceedings of the National Academy of Sciences of the United States of America·J GongD Kufe
Mar 4, 2000·International Journal of Cancer. Journal International Du Cancer·U TrefzerP Walden
Mar 4, 2000·International Journal of Cancer. Journal International Du Cancer·H M HurksM J Jager
Apr 13, 2000·International Journal of Cancer. Journal International Du Cancer·A MackensenA Lindemann
Jul 21, 2000·The Journal of Immunology : Official Journal of the American Association of Immunologists·J GongD Kufe
Nov 9, 2000·The Journal of Immunology : Official Journal of the American Association of Immunologists·S KoidoJ Gong
Jun 1, 2001·Nature Medicine·J W Fabre
Oct 31, 2001·Clinical Immunology : the Official Journal of the Clinical Immunology Society·Y TanakaJ Gong
Dec 6, 2001·The Journal of Experimental Medicine·S IbeT Blankenstein
Feb 23, 2002·The Journal of Immunology : Official Journal of the American Association of Immunologists·Shigeo KoidoJianlin Gong
Jan 23, 2003·International Journal of Hyperthermia : the Official Journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group·V MilaniR D Issels
Feb 8, 2003·The Journal of Immunology : Official Journal of the American Association of Immunologists·Jianchuan XiaJianlin Gong
Mar 21, 2003·The Journal of Immunology : Official Journal of the American Association of Immunologists·John Y KaoJian-Jun Chen
Apr 2, 2003·Cancer Immunology, Immunotherapy : CII·Tsuyoshi ItohHisakazu Yamagishi
Apr 30, 2003·Cellular Immunology·Hiroshi TanakaSuyu Shu
May 3, 2003·Molecular Therapy : the Journal of the American Society of Gene Therapy·William M SidersJohanne M Kaplan

❮ Previous
Next ❯

Citations

Sep 17, 2011·Clinical & Developmental Immunology·Shigeo KoidoHisao Tajiri
Jul 20, 2010·Immunotherapy·Telma Miyuki OshiroAlberto José da Silva Duarte
Jul 20, 2010·Immunotherapy·Richard E BeatsonJoy M Burchell
May 19, 2012·Seminars in Oncology·David AviganDonald Kufe
Mar 17, 2010·Clinical Immunology : the Official Journal of the Clinical Immunology Society·Shigeo KoidoHisao Tajiri
Apr 10, 2010·Journal of Biomedicine & Biotechnology·Shigeo KoidoHisao Tajiri
Nov 5, 2010·Clinical & Developmental Immunology·Shigeo KoidoHisao Tajiri
Feb 26, 2010·Clinical & Developmental Immunology·Shigeo KoidoHisao Tajiri
Mar 20, 2013·BioMed Research International·Elena NiccolaiAmedeo Amedei
May 3, 2016·International Journal of Molecular Sciences·Daniel Bastida-RuizMarie Cohen
May 31, 2016·International Journal of Molecular Sciences·Shigeo Koido
Jul 25, 2021·International Journal of Molecular Sciences·Inez WensNathalie Cools

❮ Previous
Next ❯

Methods Mentioned

BETA
transgenic

Related Concepts

Related Feeds

Cancer Biology: Molecular Imaging

Molecular imaging enables noninvasive imaging of key molecules that are crucial to tumor biology. Discover the latest research in molecular imaging in cancer biology in this feed.

Cancer Vaccines

Cancer vaccines are vaccines that either treat existing cancer or prevent development of a cancer.