Cancer immunotherapy: imaging assessment of novel treatment response patterns and immune-related adverse events

Radiographics : a Review Publication of the Radiological Society of North America, Inc
Jennifer J KwakHeather A Jacene

Abstract

Cancer immunotherapy is changing the imaging evaluation of cancer treatment response and treatment-related toxic effects. New emerging patterns of treatment response and treatment-related toxic effects after treatment with immunomodulating agents have been observed. Treatment response after immunomodulatory therapy can be associated with significantly delayed decrease in tumor size, and new or enlarging tumors observed soon after completion of treatment may not reflect disease progression. In addition, activation of the immune system to fight cancer may lead to unwanted autoimmune-mediated toxic effects that could be mistaken for metastatic disease or misdiagnosed as a non-treatment-related process and delay appropriate clinical management. Radiologists must recognize the novel treatment response patterns and the wide range of autoimmune toxic effects, which should not be mistaken for treatment failure or metastatic disease progression.

References

Aug 10, 2005·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Peter AttiaSteven A Rosenberg
Aug 8, 2006·Biotechnology Journal·Manfred SchusterRalf Kircheis
Jun 19, 2008·Clinical Cancer Research : an Official Journal of the American Association for Cancer Research·Jelena LazovicRussell E Jacobs
Nov 26, 2009·Clinical Cancer Research : an Official Journal of the American Association for Cancer Research·Jedd D WolchokF Stephen Hodi
Jun 8, 2010·The New England Journal of Medicine·F Stephen HodiWalter J Urba
Dec 24, 2011·Nature·Ira MellmanGlenn Dranoff
Jan 25, 2012·Clinical Cancer Research : an Official Journal of the American Association for Cancer Research·Peter A PrietoGiao Q Phan
Jun 5, 2012·The New England Journal of Medicine·Julie R BrahmerJon M Wigginton
Oct 10, 2012·Anti-cancer Drugs·Jamie C PoustMyke R Green
Oct 12, 2012·Cellular and Molecular Life Sciences : CMLS·Erik H J G AarntzenI Jolanda M de Vries
Feb 15, 2013·Investigational New Drugs·Kyung Won KimNageatte Ibrahim
Mar 6, 2013·Chest·Igor Z BarjaktarevicDiane Stover
May 31, 2013·AJR. American Journal of Roentgenology·Kyung Won KimNageatte Ibrahim
Jun 4, 2013·Cancer Treatment Reviews·Helen GogasJohn Kirkwood
Jun 5, 2013·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·David R MinorJudith Doyle
Jul 23, 2013·Advances in Cancer Research·Chunqing GuoXiang-Yang Wang
Oct 4, 2013·Clinical Cancer Research : an Official Journal of the American Association for Cancer Research·Patrick A OttCaroline Robert

❮ Previous
Next ❯

Citations

Nov 29, 2015·Magnetic Resonance Imaging Clinics of North America·Roberto García-FigueirasSandra Baleato-González
Aug 19, 2015·Clinical Nuclear Medicine·Yazan Z AlabedAnnick D Van den Abbeele
Apr 9, 2017·European Journal of Nuclear Medicine and Molecular Imaging·Annie N M WongRodney J Hicks
Mar 17, 2017·AJR. American Journal of Roentgenology·Vincenzo K WongPerry J Pickhardt
May 10, 2017·Clinical Nuclear Medicine·Roy A RaadAnna Pavlick
Jun 2, 2017·Nuclear Medicine Communications·Julien DubreuilAndrea Skanjeti
Jun 29, 2017·AJR. American Journal of Roentgenology·Gary X WangFlorian J Fintelmann
Nov 28, 2017·The British Journal of Radiology·Bhanusupriya SomarouthuAvinash Kambadakone
Apr 20, 2018·Cancer·Brett W CarterWei T Yang
Nov 14, 2017·Radiographics : a Review Publication of the Radiological Society of North America, Inc·Gary X WangFlorian J Fintelmann
Jul 12, 2018·AJR. American Journal of Roentgenology·Ailbhe C O'NeillNikhil H Ramaiya
Dec 4, 2019·The American Journal of Gastroenterology·Ethan D MillerNaga Chalasani
Aug 9, 2017·Journal of Thoracic Imaging·Brett W CarterPatricia M de Groot
Jul 10, 2019·Clinical Nuclear Medicine·Jeeban Paul DasGary A Ulaner
Nov 13, 2019·Current Opinion in Oncology·Wieland VoigtHelmut Prosch
Apr 17, 2020·Diagnostics·Vanina VaniEmanuele Neri
May 27, 2020·Abdominal Radiology·Ali PourvaziriAvinash Kambadakone
Feb 6, 2017·Abdominal Radiology·Francesco AlessandrinoDonald N Di Salvo
Jul 1, 2018·Military Medical Research·Jin-Song WangHai-Li Qian
Jan 1, 2016·Current Radiology Reports·Gerlig WidmannWerner Jaschke
Nov 28, 2018·Cancer Immunology, Immunotherapy : CII·Christos SachpekidisAntonia Dimitrakopoulou-Strauss
Feb 6, 2019·Nature Reviews. Clinical Oncology·Mirjam GerwingMoritz Wildgruber
Oct 31, 2017·Current Opinion in Urology·Jakob WeissSascha Kaufmann
Jul 29, 2017·Radiographics : a Review Publication of the Radiological Society of North America, Inc·Stephanie T ChangTerry S Desser
Jul 10, 2018·Memo·Lucian BeerHelmut Prosch
Jul 10, 2019·The Quarterly Journal of Nuclear Medicine and Molecular Imaging : Official Publication of the Italian Association of Nuclear Medicine (AIMN) [and] the International Association of Radiopharmacology (IAR), [and] Section of the Society of Radiopharmaceutica·Sofia VazTim Van den Wyngaert
Nov 11, 2019·Der Urologe. Ausg. A·F PeisenS Kaufmann
Jun 26, 2020·Journal for Immunotherapy of Cancer·Xiaoyu JiangJohn C Gore
Jan 18, 2017·Korean Journal of Radiology : Official Journal of the Korean Radiological Society·Marta Braschi-AmirfarzanMizuki Nishino
Jan 5, 2020·European Radiology Experimental·Clarisse DromainAntonia Digklia
Jul 28, 2020·Der Radiologe·Hannah SchneiderMichel Eisenblätter

❮ Previous
Next ❯

Related Concepts

Related Feeds

Autoimmune Diseases

Autoimmune diseases occur as a result of an attack by the immune system on the body’s own tissues resulting in damage and dysfunction. There are different types of autoimmune diseases, in which there is a complex and unknown interaction between genetics and the environment. Discover the latest research on autoimmune diseases here.

Cancer Vaccines

Cancer vaccines are vaccines that either treat existing cancer or prevent development of a cancer.