Cancer immunotherapy with chemoattractant peptides

Seminars in Cancer Biology
Marta Coscia, Arya Biragyn

Abstract

The chemokine/chemokine receptor network is an essential part of an intricate system of immunosurveillance and homeostasis, it promotes or suppresses neovascularization, affects and regulates directly or indirectly growth and metastasis of malignant cells. Numerous studies have been conducted to harness this network as therapeutic agents for cancer to redress the chemokine balance and control angiogenesis and tumour growth and metastasis. Second generation of immunotherapeutics and chemoattractant-based vaccines use chemokines and chemoattractant peptides to elicit antitumor immunity by a specific targeting and modulating subsets of effector leukocytes, including professional antigen presenting cells.

References

Dec 1, 1989·The Journal of Clinical Investigation·M C TerritoR Lehrer
Sep 1, 1993·The Journal of Experimental Medicine·A D Luster, P Leder
Jun 15, 1996·The Journal of Clinical Investigation·D A ArenbergR M Strieter
Jan 22, 1998·Cancer Immunology, Immunotherapy : CII·P M GuyreA L Howell
May 30, 1998·Proceedings of the National Academy of Sciences of the United States of America·I DamonB Moss
Aug 6, 1998·The Journal of Clinical Investigation·D A ArenbergR M Strieter
Jan 20, 1999·Proceedings of the National Academy of Sciences of the United States of America·J W LillardJ R McGhee
Feb 1, 2000·Immunology Today·A S LalaniG McFadden
Apr 20, 2000·Journal of the National Cancer Institute·A CorcioneV Pistoia
Oct 12, 2000·FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology·R SalcedoJ J Oppenheim
May 19, 2001·Clinical Immunology : the Official Journal of the Clinical Immunology Society·Y LeJ M Wang
Sep 19, 2001·The Journal of Experimental Medicine·D HawigerM C Nussenzweig
Oct 5, 2001·The American Journal of Pathology·M V VolinA E Koch
Dec 26, 2001·Nature Biotechnology·Tadashi KumamotoAkira Takashima
Mar 27, 2002·Nature Reviews. Immunology·Bernhard HomeyAlbert Zlotnik
Sep 11, 2002·FEBS Letters·Sigrid HatseDominique Schols
Sep 13, 2002·Immunology and Cell Biology·Shaun R McColl
Sep 13, 2002·Immunology and Cell Biology·Petra D Cravens, Peter E Lipsky
Nov 16, 2002·Journal of Interferon & Cytokine Research : the Official Journal of the International Society for Interferon and Cytokine Research·Kevin BaconUNKNOWN IUIS/WHO Subcommittee on Chemokine Nomenclature
Dec 20, 2002·Nature·Lisa M Coussens, Zena Werb
Feb 13, 2003·British Journal of Haematology·William G WierdaMaher Albitar
Jul 3, 2003·The Journal of Biological Chemistry·Lior ZilberbergAndreas Bikfalvi

❮ Previous
Next ❯

Citations

Oct 15, 2011·Cancer Gene Therapy·T Nguyen-HoaiJ Westermann
Apr 6, 2007·Expert Review of Vaccines·Chiara Dell'Agnola, Arya Biragyn
Sep 26, 2006·Advanced Drug Delivery Reviews·Violet I F Slettenaar, Julia L Wilson
Jan 26, 2008·Nature Reviews. Cancer·Jason RiceFreda K Stevenson
Jun 27, 2014·Vaccines·Iuliana D BobangaAlex Y Huang
Sep 11, 2007·Journal of Evaluation in Clinical Practice·Claire ScullinJames C McElnay
Jul 21, 2007·The Journal of Immunology : Official Journal of the American Association of Immunologists·Dolgor BaatarArya Biragyn
Nov 17, 2007·Clinical Cancer Research : an Official Journal of the American Association for Cancer Research·Yong-sheng WangYu-quan Wei
Feb 27, 2021·Veterinary Immunology and Immunopathology·Shannon S ConnardKyla F Ortved
May 12, 2009·Microvascular Research·Lucíola S BarcelosMauro M Teixeira

❮ Previous
Next ❯

Related Concepts

Related Feeds

Arterial-Venous in Development & Disease

Arterial-venous development may play a crucial role in cardiovascular diseases. Here is the latest research.

Cancer Vaccines

Cancer vaccines are vaccines that either treat existing cancer or prevent development of a cancer.

Autoimmune Diseases

Autoimmune diseases occur as a result of an attack by the immune system on the body’s own tissues resulting in damage and dysfunction. There are different types of autoimmune diseases, in which there is a complex and unknown interaction between genetics and the environment. Discover the latest research on autoimmune diseases here.

Cell Migration in Cancer and Metastasis

Migration of cancer cells into surrounding tissue and the vasculature is an initial step in tumor metastasis. Discover the latest research on cell migration in cancer and metastasis here.

Avian Influenza: Innate Immune Adjuvant

Adjuvants systems that are added to vaccines against avian influenza have be explored to enhance the innate immune system response against the virus. Here is the latest research on avian influenza and the innate immune adjuvant.

Angiogenesis Inhibitors to Treat Cancer

Cancer treatments including angiogenesis inhibitors prevent tumor cells from receiving nutrients and oxygen. Here is the latest research on angiogenesis inhibitors for the treatment of cancer.

B-Cell Leukemia (Keystone)

B-cell leukemia includes various types of lymphoid leukemia that affect B cells. Here is the latest research on B-cell leukemia.

B-Cell Lymphoma

B-cell lymphomas include lymphomas that affect B cells. This subtype of cancer accounts for over 80% of non-Hodgkin lymphomas in the US. Here is the latest research.

Apoptosis in Cancer

Apoptosis is an important mechanism in cancer. By evading apoptosis, tumors can continue to grow without regulation and metastasize systemically. Many therapies are evaluating the use of pro-apoptotic activation to eliminate cancer growth. Here is the latest research on apoptosis in cancer.

Cancer Biology: Molecular Imaging

Molecular imaging enables noninvasive imaging of key molecules that are crucial to tumor biology. Discover the latest research in molecular imaging in cancer biology in this feed.

Avian Influenza: Innate Immune Adjuvant (ASM)

Adjuvants systems that are added to vaccines against avian influenza have be explored to enhance the innate immune system response against the virus. Here is the latest research on avian influenza and the innate immune adjuvant.

Cell Migration

Cell migration is involved in a variety of physiological and pathological processes such as embryonic development, cancer metastasis, blood vessel formation and remoulding, tissue regeneration, immune surveillance and inflammation. Here is the latest research.

Apoptosis

Apoptosis is a specific process that leads to programmed cell death through the activation of an evolutionary conserved intracellular pathway leading to pathognomic cellular changes distinct from cellular necrosis

© 2022 Meta ULC. All rights reserved