Cancer incidence in the Western Australian mining industry (1996-2013)

Cancer Epidemiology
Nita Sodhi-BerryS Peters

Abstract

Miners are frequently exposed to established and potential carcinogens. We aimed to assess cancer incidence in miners relative to the general population and identify high-risk subgroups. Incident cancers in Western Australian miners (n=153,922; 86% male) during 1996-2013 were identified. Indirectly standardised incidence ratios (SIRs) were calculated and mixed-effects Poisson models were used to calculate Incidence Rate Ratios (IRRs) to identify high-risk within-cohort subgroups. Compared with the general population, the overall cancer incidence in miners (n=4194 cases) was lower for both females (SIR:0.83, 95%CI:0.74-0.92) and males (SIR:0.96, 95%CI:0.93-0.99). Overall, cancer incidence did not differ by employment duration or employment commencement time. Ever-underground work was associated with lung cancer (IRR:1.81, 95%CI:1.11-2.93). Relative to multi-ore miners, IRRs for specific cancers were significantly different when exclusively mining: iron (prostate:0.73, 95%CI:0.56-0.94); gold (lung:1.77, 95%CI:1.04-3.01 and colorectum:1.70, 95%CI:1.16-2.51); and other metals (urinary tract:1.85, 95%CI:1.03-3.31 and leukaemia:0.36, 95%CI:0.14-0.96). Working underground emerged as a significant determinant of lung cancer risk in our...Continue Reading

Citations

Feb 29, 2020·Journal of Toxicology and Environmental Health. Part B, Critical Reviews·Jody MorganAlison L Jones
Nov 2, 2019·International Journal of Epidemiology·Arthur W Bill MuskNicholas de Klerk
Oct 1, 2019·Current Medicinal Chemistry·Geir BjørklundJan Aaseth
Aug 17, 2021·Ecotoxicology and Environmental Safety·Samantha Jiménez-OyolaPaola Romero

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