Cancer of the prostate: a nutritional disease?

Urology
W R FairW D Heston

Abstract

In summary, epidemiologic and laboratory evidence increasingly demonstrate that nutritional factors, especially reduced fat intake, soy proteins, vitamin E derivatives, and selenium, may have a protective effect against prostate cancer. The experimental observation that low-fat diets and soy protein extracts may influence the progression of established tumors, rather than inhibiting etiologic factors, is particularly intriguing because it may serve to help explain the paradox whereby the incidence of clinical prostate cancer shows wide geographic variation, yet the evidence persists that the incidence of microfocal tumors is essentially the same worldwide. These observations, plus the likelihood that nutrition trials are likely to have little in the way of toxicity that would preclude their completion, argue that such trials should be performed. It is estimated that 30% to 50% of human malignancies may be related to dietary factors, and although the feasibility of trials involving low-fat diets has been proved in ongoing trials for colon and breast cancer, no similar study exists for prostate malignancy. Critics of epidemiologic research argue that data derived from case-control studies are subject to recall bias and are thus a...Continue Reading

References

Nov 15, 1977·International Journal of Cancer. Journal International Du Cancer·N BreslowH Tulinius
Oct 7, 1992·Journal of the National Cancer Institute·T Reynolds
Jan 1, 1990·The Prostate·S M FinchamC Wijayasinghe
Jan 1, 1987·Nutrition and Cancer·L KaulS L Perry
Jun 1, 1986·British Journal of Cancer·R TalaminiS Franceschi
Jan 1, 1985·The Prostate·M Y HeshmatS L Perry
Jan 1, 1984·The Prostate·W D Flanders
Jan 1, 1984·Journal of Steroid Biochemistry·E HämäläinenP Pietinen
Jan 1, 1983·Journal of Cancer Research and Clinical Oncology·G Dhom
Oct 4, 1995·Journal of the National Cancer Institute·Y WangW D Heston
Nov 13, 1993·Lancet·H AdlercreutzS Watanabe
Oct 6, 1993·Journal of the National Cancer Institute·E GiovannucciW C Willett
Apr 14, 1994·The New England Journal of Medicine·UNKNOWN Alpha-Tocopherol, Beta Carotene Cancer Prevention Study Group
Feb 16, 1994·Journal of the National Cancer Institute·P H GannM J Stampfer
Oct 1, 1996·The Journal of Urology·E L Wynder, W R Fair

❮ Previous
Next ❯

Citations

Aug 15, 2006·Current Treatment Options in Oncology·Neil Fleshner, Girish Kulkarni
Jun 1, 2005·Urology·Serdar GoktasSelahattin Bedir
Dec 1, 2001·Clinica Chimica Acta; International Journal of Clinical Chemistry·Peter S Bunting
Jul 10, 2002·Cancer Detection and Prevention·Kushlani GunawardenaA Wayne Meikle
Oct 17, 2001·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·D M ParkinS S Devesa
Jun 24, 1999·Journal of Clinical Pharmacy and Therapeutics·R Y Henry, D O'Mahony
Aug 9, 2001·Journal of Clinical Pharmacy and Therapeutics·J GeorgeM J Kendall
Feb 22, 2002·BJU International·J-P Meyer, D A Gillatt
Nov 7, 1998·British Journal of Urology·J HempstockN J George
Apr 23, 2005·Journal of Environmental Science and Health. Part C, Environmental Carcinogenesis & Ecotoxicology Reviews·Junjian Z Chen, Fred F Kadlubar
Jan 1, 1999·Journal of Medicinal Food·J HempstockN J George
May 18, 1999·Current Opinion in Oncology·E J Small
Apr 6, 2000·Psychosomatics·E J KunkelL G Gomella
Sep 26, 2008·Integrative Cancer Therapies·Gordon A SaxeTracy M Downs
Oct 6, 2000·Environmental Health Perspectives·J M MolineP J Landrigan
Mar 25, 2014·Medical Oncology·Ugur UyeturkAdnan Gucuk
Sep 14, 2010·Progrès en urologie : journal de l'Association française d'urologie et de la Société française d'urologie·F Desgrandchamps, L Bastien
Feb 3, 2009·Cancer Letters·Lakshmipathi KhandrikaHari K Koul
Sep 26, 2007·Cancer·Neil Fleshner, Alexandre R Zlotta
Nov 10, 2004·Urology·Lilli B LinkL H Lumey
Mar 12, 2003·The Journal of Urology·Kenan SaglamSerdar Göktaş
Apr 5, 2000·Current Problems in Cancer·G C Morton
May 20, 1999·The Journal of Urology·A M Kamat, D L Lamm
Sep 6, 2005·Cancer Detection and Prevention·Kushlani GunawardenaA Wayne Meikle
Aug 30, 2001·Hematology/oncology Clinics of North America·S E DePrimoJ D Brooks
Jul 12, 2002·The Urologic Clinics of North America·Neil E Fleshner
May 5, 2004·The Urologic Clinics of North America·Jack H Mydlo
Feb 22, 2011·Free Radical Biology & Medicine·Sharon E CampbellKoyamangalath Krishnan
Jun 9, 2006·The Aging Male : the Official Journal of the International Society for the Study of the Aging Male·K P Kleinman, J B McKinlay

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.