PMID: 9178802May 16, 1997Paper

Cancer risk after renal transplantation in Japan

International Journal of Cancer. Journal International Du Cancer
Y HoshidaK Aozasa

Abstract

Excess of cancer in patients receiving renal transplantation is well-known in Western countries, but information in Japan remains limited. Our study examined whether excess risk is found in patients receiving renal transplantation in Japan. Between 1970 and 1995, 1155 males and 589 females underwent renal transplantation in 6 hospitals, and a total of 12,982 person-years of observation was accumulated. Malignancies developed in 2.6% of patients; O/E ratio was 2.78. Median interval from renal transplantation to tumor development was 58 months. The interval in the patients receiving medication with cyclosporine-A (CyA) (median, 42.5 months) was significantly shorter than that with non-CyA (median, 95.5 months). Median age at the diagnosis of malignancy was 40 years, which is much younger than that in the general population. Relative risk was highest in renal cancer, followed by thyroid cancer, malignant lymphoma and uterine cancer. A distribution of malignancies was different from that reported from Western countries. These findings showed the excess risk of malignancies in Japan with renal transplants, especially in male patients, similar to that observed in Western countries, though the types of malignancy were different.

References

Jan 1, 1989·British Journal of Industrial Medicine·M J Gardner
Aug 1, 1974·Computers and Biomedical Research, an International Journal·R R Monson
Jun 27, 1995·Transplantation·S B GayaP D Mason
Jan 17, 1995·International Journal of Cancer. Journal International Du Cancer·S A BirkelandL Frödin
Feb 15, 1994·International Journal of Cancer. Journal International Du Cancer·M InoueT Kitoh

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Citations

Jul 1, 2014·Cancers·Janice E Ma, Jerry D Brewer
Feb 6, 2014·British Journal of Cancer·L YanZ-Y Jiang
Nov 24, 2001·Archives of Disease in Childhood·H M CoutinhoH S Heymans
Nov 5, 2010·Biomedical Papers of the Medical Faculty of the University Palacký, Olomouc, Czechoslovakia·Lucie KalinovaPetr Bachleda
Sep 25, 2008·Nature Reviews. Cancer·Ervin H Epstein
Jun 3, 2011·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·Wei-Hsuan LiHan-Nan Liu
Dec 25, 2012·Expert Review of Anticancer Therapy·Pierre-Antoine DuguéElsebeth Lynge
Dec 2, 2009·Journal of the Chinese Medical Association : JCMA·Po-Lin ChenAn-Hang Yang
Jan 5, 1999·Liver Transplantation and Surgery : Official Publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society·K SaeianM B Adams
Dec 14, 2004·Cancer·Yann NeuzilletEric Lechevallier
Jun 18, 2004·Kidney International·Mahendra L AgraharkarVahakn B Shahinian
Mar 13, 2010·Actas urologicas españolas·C di Capua SacotoJ F Jiménez Cruz
May 18, 2011·The Journal of Urology·Michael LeveridgeAntonio Finelli
Sep 16, 2008·Transplantation Proceedings·N ArichiY Ichikawa
Sep 16, 2008·Transplantation Proceedings·T AtivitavasV Mavichak
Jan 5, 2002·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·Martin ZeierEberhard Ritz
Sep 4, 2007·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·Diego SerrainoUNKNOWN Immunosuppression and Cancer Study Group
May 30, 2007·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·Aparna Padiyar, Donald E Hricik
Jun 19, 2007·Urology·Yao-Min HungJui-Chen Chang
May 16, 2009·International Journal of Cancer. Journal International Du Cancer·Claire M Vajdic, Marina T van Leeuwen
Feb 18, 2009·Transplant International : Official Journal of the European Society for Organ Transplantation·Man Ki JuYu Seun Kim
Aug 25, 2006·International Journal of Cancer. Journal International Du Cancer·Sam M Mbulaiteye, Eric A Engels
Oct 1, 2008·Liver Transplantation : Official Publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society·Fredrik AbergHelena Isoniemi
Oct 5, 2006·Transplant International : Official Journal of the European Society for Organ Transplantation·Michèle KesslerFrancis Guillemin
Apr 5, 2007·Cancer·Tetsuya ImaoAkihiko Okuyama
Oct 19, 2011·International Journal of Urology : Official Journal of the Japanese Urological Association·Ryuto NakazawaTatsuya Chikaraishi
Aug 14, 2012·American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons·C Y CheungK F Chau
Jul 28, 2010·American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons·D CollettC Watson
May 18, 2011·Transplant International : Official Journal of the European Society for Organ Transplantation·Jeong-Kye HwangJi-Il Kim
Apr 23, 2014·Clinical Transplantation·Ji Hyun KimSu-Kil Park
Jun 28, 2005·Critical Reviews in Oncology/hematology·Amado Andrés
Jun 28, 2005·Critical Reviews in Oncology/hematology·Ricky A Sharma, Michael J Browning
Dec 18, 2013·Journal of the American Academy of Dermatology·Gyeong-Hun ParkSung-Gyu Lee
Oct 16, 2012·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·Pierluca PiselliUNKNOWN Immunosuppression and Cancer Study Group
Apr 22, 2015·Transplantation Proceedings·Y TomimaruH Nagano
May 27, 1999·The Journal of Dermatology·S AnzaiS Takahashi
Dec 31, 1997·The Journal of Dermatology·S AnzaiS Takayasu
Mar 29, 2001·International Journal of Cancer. Journal International Du Cancer·Y HoshidaK Aozasa
Dec 9, 2000·Transplant International : Official Journal of the European Society for Organ Transplantation·L KyllönenE Pukkala

❮ Previous
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