Cancer stem cell markers in breast neoplasias: their relevance and distribution in distinct molecular subtypes.

Virchows Archiv : an International Journal of Pathology
Fernando SchmittJoana Paredes

Abstract

The identification and characterization of cancer stem cells might lead to more effective control of neoplastic disease, by directing therapies to the most aggressive cells. For that reason, the identification of cancer stem cells (CSCs) in breast tumours is one of the priorities in breast cancer research, which has resulted in many studies attempting to identify their presence based on the expression of specific molecular markers. In this review, we describe the main molecular markers that have been identified as being able to recognise CSCs in breast carcinomas, the major molecular pathways that regulate CSCs and their association with the different molecular subtypes.

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Citations

Mar 13, 2013·Proceedings of the National Academy of Sciences of the United States of America·Yuh-Jin LiangSen-itiroh Hakomori
Sep 21, 2013·Biomarkers in Medicine·György VáradyBalázs Sarkadi
Jan 16, 2016·Histopathology·Chieh-Yu LinKimberly H Allison
Jul 3, 2016·Breast Cancer Research : BCR·Yuichiro MiyoshiUNKNOWN Collaborative Study Group of Scientific Research of the Japanese Breast Cancer Society
Mar 28, 2013·ISRN Oncology·Aamir Ahmad
Nov 27, 2015·Breast Cancer : Basic and Clinical Research·Valéria B de Souza, André A Schenka
Oct 30, 2016·The International Journal of Biological Markers·Zhu WangJie Chen
Mar 28, 2018·Cancer Biology & Therapy·Liting JinXiaojiang Cui
Jan 6, 2021·International Journal of Molecular Sciences·Marta Teixeira PintoJoana Paredes

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