Candida auris , an Agent of Hospital-Associated Outbreaks: Which Challenging Issues Do We Need to Have in Mind?

Microorganisms
Raquel SabinoFrancisco Antunes

Abstract

The emergence of Candida auris is considered as one of the most serious problems associated with nosocomial transmission and with infection control practices in hospital environment. This multidrug resistant species is rapidly spreading worldwide, with several described outbreaks. Until now, this species has been isolated from different hospital surfaces, where it can survive for long periods. There are multiple unanswered questions regarding C. auris, such as prevalence in population, environmental contamination, effectiveness of infection prevention and control, and impact on patient mortality. In order to understand how it spreads and discover possible reservoirs, it is essential to know the ecology, natural environment, and distribution of this species. It is also important to explore possible reasons to this recent emergence, namely the environmental presence of azoles or the possible effect of climate change on this sudden emergence. This review aims to discuss some of the most challenging issues that we need to have in mind in the management of C. auris and to raise the awareness to its presence in specific indoor environments as hospital settings.

References

Jan 1, 1988·Journal of Medical and Veterinary Mycology : Bi-monthly Publication of the International Society for Human and Animal Mycology·F BistoniA Cassone
Jan 16, 2007·Clinical Microbiology Reviews·M A Pfaller, D J Diekema
Feb 6, 2009·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Mi-Na KimDong Wook Ryang
Jun 8, 2011·Microbiology and Molecular Biology Reviews : MMBR·Rebecca S ShapiroLeah E Cowen
Jul 1, 2011·Journal of Clinical Microbiology·Wee Gyo LeeHee-Chang Jang
Dec 1, 2012·The Journal of Hospital Infection·J A OtterG L French
Jan 11, 2013·Virulence·François L MayerBernhard Hube
Sep 21, 2013·Emerging Infectious Diseases·Anuradha ChowdharyJacques F Meis
Dec 21, 2013·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·A ChowdharyJ F Meis
Mar 13, 2014·Therapeutics and Clinical Risk Management·Nur Yapar
Jun 26, 2014·Emerging Infectious Diseases·Rindidzani E MagoboNelesh P Govender
May 20, 2015·Emerging Infectious Diseases·Maha EmaraRitu Bafna
Jul 21, 2015·Annals of the New York Academy of Sciences·David S Perlin
Sep 9, 2015·BMC Genomics·Sharanya ChatterjeeUtpal S Tatu
Nov 10, 2015·Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases·Anupam PrakashAnuradha Chowdhary
Jan 8, 2016·Infectious Disease Clinics of North America·Todd P McCarty, Peter G Pappas
Jan 27, 2016·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Peter G PappasJack D Sobel
Jul 28, 2016·The Journal of Infection·Belinda CalvoArnaldo Lopes Colombo
Oct 26, 2016·Antimicrobial Resistance and Infection Control·Silke SchelenzMatthew C Fisher
Nov 25, 2016·Journal of Clinical Microbiology·Masako MizusawaSean X Zhang
Dec 17, 2016·Emerging Infectious Diseases·Soraya E Morales-LópezJosé Y Rodríguez
Dec 19, 2016·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Shawn R LockhartAnastasia P Litvintseva
Dec 29, 2016·American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons·S VallabhaneniT M Chiller
Jan 19, 2017·Emerging Infectious Diseases·Leighann SherryRiina Rautemaa-Richardson
Jan 31, 2017·Revista iberoamericana de micología·Alba Cecilia Ruiz GaitánJavier Pemán
Feb 17, 2017·Medical Mycology·Andrew M BormanElizabeth M Johnson
Mar 24, 2017·The Journal of Antimicrobial Chemotherapy·Shivaprakash M RudramurthyAnup Ghosh
May 10, 2017·Antimicrobial Agents and Chemotherapy·Elizabeth L BerkowShawn R Lockhart
May 19, 2017·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Marwan M AzarVirginia M Pierce
May 26, 2017·Journal of Clinical Microbiology·Milena KordalewskaDavid S Perlin
Jun 6, 2017·The Journal of Infection·Turkiya Al-SiyabiBadriya Al'Adawi
Jun 28, 2017·Infection and Drug Resistance·Smita Sarma, Shalini Upadhyay
Aug 18, 2017·Infection and Drug Resistance·Elizabeth L Berkow, Shawn R Lockhart
Sep 25, 2017·The Journal of Hospital Infection·M BiswalA Chakrabarti
Nov 17, 2017·Clinical Microbiology Reviews·Anna Jeffery-SmithColin S Brown

❮ Previous
Next ❯

Methods Mentioned

BETA
PCR

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

JAMA : the Journal of the American Medical Association
Suzanne F Bradley
CMAJ : Canadian Medical Association Journal = Journal De L'Association Medicale Canadienne
Ilan S Schwartz, T C Dingle
JAMA : the Journal of the American Medical Association
Suzanne F Bradley
© 2021 Meta ULC. All rights reserved