Nov 20, 2013

Candida glabrata: a review of its features and resistance

European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology
C F RodriguesM Henriques

Abstract

Candida species belong to the normal microbiota of the oral cavity and gastrointestinal and vaginal tracts, and are responsible for several clinical manifestations, from mucocutaneous overgrowth to bloodstream infections. Once believed to be non-pathogenic, Candida glabrata was rapidly blamable for many human diseases. Year after year, these pathological circumstances are more recurrent and problematic to treat, especially when patients reveal any level of immunosuppression. These difficulties arise from the capacity of C. glabrata to form biofilms and also from its high resistance to traditional antifungal therapies. Thus, this review intends to present an excerpt of the biology, epidemiology, and pathology of C. glabrata, and detail an approach to its resistance mechanisms based on studies carried out up to the present.

  • References139
  • Citations50

References

  • References139
  • Citations50

Citations

Mentioned in this Paper

Entire Oral Cavity
Decreased Immunologic Activity [PE]
Tract
Craspedia glabrata
Pathogenic Organism
Antibiotics, Antifungal
Cordia glabrata
Cornus glabrata
Candida glabrata
Gastrointestinal Neoplasms

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