Candida parapsilosis bloodstream infection in pediatric oncology patients: results of an epidemiologic investigation

Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America
Brunella PosteraroGiovanni Fadda

Abstract

To investigate an outbreak of Candida parapsilosis bloodstream infections (BSIs) involving three patients admitted to a pediatric oncology unit between April and June 2002. After the third case was documented, cultures were performed of the hands of all medical and paramedical staff members in the pediatric oncology unit and of environmental surfaces in the rooms occupied by the three patients. Electrophoretic karyotyping with pulsed-field gel electrophoresis and arbitrarily primed polymerase chain reaction were used to assess the genetic relatedness among C. parapsilosis isolates. The three cases of C. parapsilosis BSI were diagnosed based on blood cultures performed during a 38-day period. Evidence of prior C parapsilosis colonization of the gastrointestinal tract was present in only the first case. Each patient had an indwelling central venous catheter (CVC), which was promptly removed, and semiquantitative catheter tip cultures also revealed C. parapsilosis. None of the 30 environmental cultures performed was positive for C. parapsilosis, but the fungus was isolated from the hands of 6 of the 20 nurses tested. Both molecular typing methods revealed identical DNA fingerprinting patterns for all 13 patient isolates (7 from bl...Continue Reading

References

Jun 9, 1977·The New England Journal of Medicine·D G MakiH W Sarafin
Jun 1, 1995·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·M A Pfaller
Jan 1, 1995·Diagnostic Microbiology and Infectious Disease·M A PfallerR J Hollis
Feb 1, 1994·Journal of Clinical Microbiology·M L BranchiniH D Isenberg
May 1, 1996·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·M A Pfaller
Jun 1, 1997·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·D Abi-SaidS Vartivarian
May 25, 2002·Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America·Stefania BocciaGiovanni Fadda
Jun 29, 2002·Journal of Clinical Microbiology·Antonella LupettiSonia Senesi

❮ Previous
Next ❯

Citations

May 31, 2012·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·G PulcranoM R Catania
Apr 27, 2011·Antimicrobial Agents and Chemotherapy·A P SilvaA G Rodrigues
Aug 8, 2012·BMJ Open·Lourdes das Neves MirandaAnna Sara Levin
Dec 4, 2009·European Journal of Pediatrics·Rigoberto Hernández-CastroAntonio Lavalle-Villalobos
Jun 26, 2013·Revista iberoamericana de micología·Laura Judith Marcos-ZambranoJesús Guinea
Nov 6, 2007·British Journal of Haematology·Penelope D Barnes, Kieren A Marr
Nov 15, 2013·Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America·J Michael KlatteMary Anne Jackson
Feb 11, 2014·Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases·J Guinea
Jun 16, 2006·Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases·A SimonK Beutel
Feb 13, 2009·Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases·M A GhannoumJ A Vazquez
Sep 11, 2004·Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America·Daniel J Diekema, Michael A Pfaller
Oct 14, 2009·Critical Reviews in Microbiology·Eveline C van AsbeckDavid A Stevens
Nov 22, 2008·Scandinavian Journal of Infectious Diseases·Anna Brillowska-DabrowskaM C Arendrup
Aug 16, 2017·Scientific Reports·Lisa LombardiGeraldine Butler
Jul 20, 2016·World Journal of Gastroenterology : WJG·Elio CastagnolaAlfredo Guarino
Feb 11, 2021·The Pediatric Infectious Disease Journal·Anna Carlota Mott BarrientosHeloisa Helena Sousa Marques

❮ Previous
Next ❯

Related Concepts

Related Feeds

Candida albicans

Candida albicans is an opportunistic, fungal pathogen of humans that frequently causes superficial infections of oral and vaginal mucosal surfaces of debilitated and susceptible individuals. Discover the latest research on Candida albicans here.

Candidiasis

Candidiasis is a common fungal infection caused by Candida and it can affect many parts for the body including mucosal membranes as well as the gastrointestinal, urinary, and respiratory tracts. Here is the latest research.

Candidiasis (ASM)

Candidiasis is a common fungal infection caused by Candida and it can affect many parts for the body including mucosal membranes as well as the gastrointestinal, urinary, and respiratory tracts. Here is the latest research.