Candiduria: Evidence-based approach to management, are we there yet?

Journal de mycologie médicale
W A Alfouzan, R Dhar

Abstract

Candiduria is considered one of the most controversial issues in patient management. Neither the diagnosis nor the optimal treatment options are standardized. This is further complicated by lack of defined laboratory criteria for diagnosis as most of the studies were set for bacterial rather than fungal urinary tract infection (UTI). Furthermore, since Candida species is a known commensal of the genitourinary tract its presence in the urine sample adds ambiguity to making a definitive diagnosis of candidal UTI. Guidelines for diagnosis and management of candiduria have changed considerably over the past decades. In 1960s, the condition was believed to be benign with no intervention required. However, over the years new dimensions were added to address the issues associated with candiduria until the latest Infectious Diseases Association of America (IDSA) guidelines were published in 2009, which indicated that there was an increase in the incidence of candiduria caused by more resistant non-Candida albicans species. Further complicating the issue is the observation that candiduria may be the only indicator of a more serious invasive candidiasis, especially in immunocompromised patients. Long-term urinary catheterization is consi...Continue Reading

Citations

Oct 10, 2018·Infection and Immunity·Alison CoadyKathryn A Patras
Oct 20, 2018·Hospital Practice·Javier Pemán, Alba Ruiz-Gaitán
Jun 19, 2018·Indian Journal of Critical Care Medicine : Peer-reviewed, Official Publication of Indian Society of Critical Care Medicine·Sai SaranAfzal Azim
Apr 23, 2020·Canadian Journal of Microbiology·Jonathas Sales de OliveiraMarcos Fábio Gadelha Rocha
Oct 28, 2019·World Journal of Urology·Zekaver Odabasi, Ali Mert
Feb 20, 2021·Infection and Drug Resistance·Zhengxin HeFukun Wang
May 25, 2021·Journal of Infection and Chemotherapy : Official Journal of the Japan Society of Chemotherapy·Jun Kamei, Shingo Yamamoto

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