Canine chronic renal disease: prevalence and types of glomerulonephritis in the dog

Kidney International
D F MacdougallV Cattell

Abstract

In a prospective survey, one hundred and eleven dogs with canine chronic renal disease, presenting to 24 veterinary practices in East Anglia and the West Midlands (geographical area 8,600 square miles) were identified. More than 20 different breeds were represented. In 76 cases, clinical details, blood and urine biochemistry, serology and kidney tissue for light and electron microscopy, and immunohistochemistry were obtained. Forty (52%) had glomerular (GN) and 36 (48%) non-glomerular (NGN) disease. Types of GN identified were (W.H.O. classification, number of cases in brackets): focal glomerulonephritis (gn) (5), diffuse mesangial proliferative gn (8), diffuse endocapillary proliferative gn (2), mesangiocapillary gn type I (8), diffuse crescentic gn (1), diffuse sclerosing gn (7), amyloid (6), unclassifiable gn (3). Eight dogs with GN and 13 with NGN had extra-renal lesions. In only one GN case (bacterial endocarditis) was the etiology clear. Proteinuria, but not age, breed, sex, serum creatinine or hematuria, discriminated between GN and NGN groups. This prospective survey identifies GN, with morphological types as found in humans, as a common cause of canine chronic renal disease.

References

Jan 1, 1977·Veterinary Pathology·R Müller-Peddinghaus, G Trautwein
Jan 1, 1975·Veterinary Pathology·B P StuartR W Thomassen
Mar 4, 1972·The Veterinary Record·R E Halliwell, W F Blakemore
Mar 14, 1981·The Veterinary Record·S C Hathaway, T W Little
Aug 29, 1981·The Veterinary Record·A P Steward, D F Macdougall
Nov 1, 1959·Circulation Research·B HIGHMANJ ROSHE

❮ Previous
Next ❯

Citations

Feb 1, 1993·Veterinary Immunology and Immunopathology·C H HarrisS Z Shapiro
May 6, 2008·Journal of Feline Medicine and Surgery·Joanna D WhiteRichard Malik
Oct 3, 1999·Veterinary Immunology and Immunopathology·N C Pedersen
Oct 1, 1994·Zentralblatt für Veterinärmedizin. Reihe A·M VilafrancaI Nolte
Dec 1, 1994·Zentralblatt für Veterinärmedizin. Reihe A·M VilafrancaG Trautwein
Jul 1, 1995·Journal of Veterinary Internal Medicine·S L VadenW Crowell
Mar 29, 2008·Journal of Veterinary Internal Medicine·O CortadellasA Bayón
Feb 24, 2012·Journal of Veterinary Internal Medicine·M B NabityJ S Suchodolski
Sep 1, 1995·In Vitro Cellular & Developmental Biology. Animal·D Ennulat, S A Brown
Oct 13, 2015·Journal of Veterinary Emergency and Critical Care·Carrie R WhitePhilip R Fox
Jul 26, 2011·Topics in Companion Animal Medicine·Shelly L Vaden
Mar 11, 2011·Journal of Comparative Pathology·R KobayashiK Shirota
Jan 22, 2011·The Veterinary Clinics of North America. Small Animal Practice·Meryl P Littman
Oct 14, 2009·Research in Veterinary Science·A YabukiO Yamato
Oct 26, 2005·The Journal of Small Animal Practice·G F Grauer
May 8, 2013·Journal of Veterinary Internal Medicine·D G O'NeillD C Brodbelt
Mar 8, 2013·Journal of Veterinary Emergency and Critical Care·Rebecca F GeddesJonathan Elliott
Mar 19, 2014·Journal of Veterinary Internal Medicine·D J Polzin, L D Cowgill
Dec 8, 1998·Clinical Techniques in Small Animal Practice·S A BrownJ A Barsanti
Sep 4, 2015·The Journal of Small Animal Practice·J L PouchelonN Van Israël
May 7, 2011·The Veterinary Journal·Annette L Litster
Jul 1, 1994·The Veterinary Clinics of North America. Small Animal Practice·R Nichols
Oct 22, 2013·Revista brasileira de parasitologia veterinária = Brazilian journal of veterinary parasitology : Órgão Oficial do Colégio Brasileiro de Parasitologia Veterinária·Jamile Prado dos SantosMaria Aparecida da Gloria Faustino
Mar 1, 2012·Journal of Veterinary Diagnostic Investigation : Official Publication of the American Association of Veterinary Laboratory Diagnosticians, Inc·Juan D García-MartínezSilvia Martínez-Subiela
Apr 7, 2018·Journal of Animal Physiology and Animal Nutrition·L F BöswaldB Dobenecker
Jul 5, 2006·American Journal of Veterinary Research·Mark J AciernoLinda A Ross
Nov 30, 2010·Journal of Veterinary Science·Ji-Young YheeJung-Hyang Sur
Jul 17, 2013·The Journal of Veterinary Medical Science·Hiroshi BabaYumi Une
May 5, 2010·Journal of the American Animal Hospital Association·Jeffrey Ruth
Aug 30, 2008·Journal of Veterinary Dentistry·Zlatko PavlicaUros Skaleric
Dec 2, 2017·Journal of Veterinary Internal Medicine·A ShipovG Segev
Jan 15, 2020·Journal of Veterinary Research·Barbara SzczepankiewiczZbigniew Szewczuk
Nov 10, 2020·Journal of Veterinary Internal Medicine·Bianca N LourençoKate E Creevy
Jun 6, 2021·Research in Veterinary Science·H MiyakawaN Takemura

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.