Canine gastric adenocarcinoma and leiomyosarcoma: a retrospective study of 21 cases (1986-1999) and literature review

Journal of the American Animal Hospital Association
Heather M Swann, David E Holt

Abstract

This retrospective study describes the clinical course, treatment, and outcome of 21 dogs with gastric adenocarcinomas (n=19) and leiomyosarcomas (n=2). Medical records from 1986 to 1999 were reviewed for signalment, weight, diagnosis, tumor location, clinical signs, radiographic imaging procedures, surgical procedures, chemotherapy, duration of follow-up monitoring, outcome, cause of death, metastatic rate, metastatic sites, and method of detection of metastasis. Fourteen of 19 (74%) dogs with gastric adenocarcinomas had metastasis. Metastatic sites included gastric lymph nodes, omentum, liver, duodenum, pancreas, spleen, esophagus, adrenal glands, and lungs. Both cases of a gastric leiomyosarcoma had metastatic disease involving the liver (n=2) and duodenum (n=1). Surgery, consisting of either a Billroth I or a gastrojejunostomy, provided immediate relief of the gastric outflow obstruction and clinical improvement in the early postoperative period. The beneficial effects of chemotherapy alone or adjuvant chemotherapy are still unknown. Recurrence of clinical signs 3 days to 10 months after surgery caused all owners to elect euthanasia. The long-term prognosis for most cases of gastric adenocarcinomas and leiomyosarcomas is po...Continue Reading

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Citations

Mar 22, 2014·The Journal of Veterinary Medical Science·Hee-Chun LeeDong-In Jung
Jul 3, 2009·Journal of the American Animal Hospital Association·Joao F de Brito GalvaoJose A Ramos-Vara
Jan 18, 2016·Journal of Comparative Pathology·I AmorimF Gärtner
Jun 23, 2012·The Veterinary Clinics of North America. Small Animal Practice·Michael D Willard
Dec 17, 2008·Topics in Companion Animal Medicine·Michael D Willard
Sep 20, 2005·The Journal of Small Animal Practice·M Dell'OrcoP Roccabianca
Aug 7, 2009·Journal of Veterinary Internal Medicine·S D TaylorN Pusterla
Jun 22, 2010·Journal of Veterinary Internal Medicine·M S LeibE S Herring
Sep 3, 2014·Australian Veterinary Journal·H R BaronR J T Doneley
Apr 1, 2016·Journal of the American Veterinary Medical Association·Victoria E WatsonDaniel R Rissi
May 31, 2016·Journal of Veterinary Internal Medicine·L K MarleyY S Nout-Lomas
Aug 24, 2016·Veterinary and Comparative Oncology·S HugenP J J Mandigers
Jan 20, 2005·Veterinary Pathology·P Labelle, H E V De Cock
Jan 4, 2019·Journal of the American Veterinary Medical Association·Tonje Seim-WikseCharlotte R Bjørnvad
Mar 22, 2013·Acta Veterinaria Scandinavica·Tonje Seim-WikseEllen Skancke
Sep 26, 2013·Journal of Zoo and Wildlife Medicine : Official Publication of the American Association of Zoo Veterinarians·Angelique LeoneJulia A Conway
Dec 19, 2018·JFMS Open Reports·Kirsty HartSabela Atencia
Aug 21, 2018·Veterinary Radiology & Ultrasound : the Official Journal of the American College of Veterinary Radiology and the International Veterinary Radiology Association·Toshiyuki TanakaShohei Kurokawa
Oct 30, 2020·Topics in Companion Animal Medicine·Vincenzo MontinaroGiorgio Romanelli
Dec 18, 2020·The Journal of Veterinary Medical Science·Aki OhmiHajime Tsujimoto
Apr 4, 2021·Animals : an Open Access Journal From MDPI·Francesco SimeoniMassimo Vignoli
May 15, 2021·Veterinary Radiology & Ultrasound : the Official Journal of the American College of Veterinary Radiology and the International Veterinary Radiology Association·Melonie ZuercherAmandine Lejeune

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