Canine intranasal tumours treated with alternating carboplatin and doxorubin in conjunction with oral piroxicam: 29 cases

Veterinary and Comparative Oncology
Matthew J WoodruffPeter Bennett

Abstract

Few veterinary studies have evaluated the response to chemotherapy treatment of canine intranasal tumours, while many have focused on the efficacy of radiation therapy. Given the higher costs and limited access to radiation therapy, alternative treatment options are needed. The study describes a cohort of dogs with histologically confirmed intranasal tumours treated with chemotherapy as a sole therapy. This retrospective study was conducted using data from the Melbourne Veterinary Specialist Centre (MVSC) database between 2004 and 2017. Dogs with a histologically confirmed intranasal tumour who received chemotherapy treatment were included. Signalment, presenting signs, tumour type, chemotherapy details, adverse events (AEs) and survival times were reviewed. Twenty-nine dogs met the inclusion criteria. Overall median survival time for dogs in the study was 234 days (range 12-1698 days). Median survival for dogs with adenocarcinoma or carcinoma (n = 12) was 280 days, transitional cell carcinoma (n = 6) 163 days, squamous cell carcinoma, anaplastic carcinoma or undifferentiated carcinoma (n = 7) 59 days and all sarcomas (n = 4) 448 days. Adverse events were reported following 28% of treatments and 69% of dogs experienced at least...Continue Reading

References

Jan 1, 1981·Cancer·A B MillerA Winkler
Dec 24, 1997·Veterinary Radiology & Ultrasound : the Official Journal of the American College of Veterinary Radiology and the International Veterinary Radiology Association·S E LanaS J Withrow
Oct 16, 1999·Veterinary Radiology & Ultrasound : the Official Journal of the American College of Veterinary Radiology and the International Veterinary Radiology Association·T A LaDueD E Thrall
Dec 21, 2004·Veterinary Radiology & Ultrasound : the Official Journal of the American College of Veterinary Radiology and the International Veterinary Radiology Association·Susan E LanaSusan M LaRue
Aug 3, 2006·Journal of the American Veterinary Medical Association·Kenneth M RassnickOrna Kristal
Jun 11, 2009·Veterinary Radiology & Ultrasound : the Official Journal of the American College of Veterinary Radiology and the International Veterinary Radiology Association·William M AdamsThomas C Havighurst
Jun 2, 2011·The Journal of Small Animal Practice·S M MurphyD E Bjorling
May 31, 2013·The Journal of Small Animal Practice·S L MasonL Blackwood
Feb 25, 2017·Veterinary Radiology & Ultrasound : the Official Journal of the American College of Veterinary Radiology and the International Veterinary Radiology Association·Cassie N LuxSarah Puchalski

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Citations

Jul 28, 2020·The Journal of Small Animal Practice·J R Mortier, L Blackwood
Jul 22, 2020·Topics in Companion Animal Medicine·Roberto TamburroMassimo Vignoli
Jun 17, 2021·The Journal of Small Animal Practice·V Merino-GutierrezF Clemente-Vicario

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