Canine prostate: contrast-enhanced US-guided radiofrequency ablation with urethral and neurovascular cooling--initial experience.

Radiology
Ji-Bin LiuEthan J Halpern

Abstract

To prospectively evaluate in a canine model contrast material-enhanced ultrasonography (US) for guiding and monitoring radiofrequency (RF) ablation of the entire prostate, with urethral and vascular cooling to protect the surrounding structures. After approval by the institutional animal use and care committee, an RF electrode was used to ablate the entire prostate in 15 dogs. During ablation, pulse-inversion harmonic US was performed by using an endocavitary probe after an intravenous bolus injection (0.04 mL/kg) and infusion (0.015 muL/kg/min) of a US contrast agent. In group 1 (n = 4), no cooling protection was used during ablation. In group 2 (n = 5), urethral and bladder protection was provided by inserting a 12-F catheter infused with cold saline (8 degrees C +/- 4 [standard deviation]) at a rate of 100 mL/min. In group 3 (n = 6), further protection of the neurovascular bundles (NVBs) was provided by infusing cold saline (8 degrees C +/- 4) into the iliac arteries at a rate of 50 mL/min by means of catheterization of the femoral artery. Pathologic findings among the three groups were compared by using the Wilcoxon rank sum test. The average volumes of prostate ablation achieved in the three groups were 96.6%, 91.9%, and 9...Continue Reading

References

Sep 1, 1991·International Journal of Radiation Oncology, Biology, Physics·C A LawtonS R Doggett
Apr 1, 1995·Journal of Endourology·G R Fournier, P Narayan
Jan 1, 1993·European Urology·M DevonecS St Clair Carter
Aug 28, 1996·JAMA : the Journal of the American Medical Association·G S GerberG W Chodak
Nov 1, 1996·The Urologic Clinics of North America·J C BlaskoP D Grimm
Jan 1, 1997·European Urology·R Thiel, R Ackermann
Sep 6, 2001·Journal of Vascular and Interventional Radiology : JVIR·S Nahum Goldberg, D E Dupuy
May 10, 2003·International Journal of Radiation Oncology, Biology, Physics·Jonathan I IzawaLouis L Pisters
Jun 14, 2003·Prostate Cancer and Prostatic Diseases·S SagiM S Michel
Sep 6, 2006·The Journal of Urology·Ji-Bin LiuBarry B Goldberg

❮ Previous
Next ❯

Citations

Nov 19, 2010·Radiology·Stephen B Solomon, Stuart G Silverman
Jan 28, 2015·Theriogenology·Luana Azevedo de FreitasLúcia Daniel Machado da Silva
Jul 28, 2013·Journal of Ultrasound in Medicine : Official Journal of the American Institute of Ultrasound in Medicine·Dong Hyun YooSeung Hyup Kim
Aug 18, 2018·Journal of Ultrasound in Medicine : Official Journal of the American Institute of Ultrasound in Medicine·Andre L de Castro AbreuMittul Gulati
Aug 30, 2018·Current Urology Reports·Akbar N AshrafiAndre L de Castro Abreu
Mar 17, 2020·Minimally Invasive Therapy & Allied Technologies : MITAT : Official Journal of the Society for Minimally Invasive Therapy·Li JiaHuang Jin

❮ Previous
Next ❯

Related Concepts

Related Feeds

Bladder Carcinoma In Situ

Bladder Carcinoma In Situ is a superficial bladder cancer that occurs on the surface layer of the bladder. Discover the latest research on this precancerous condition in this feed.