Canine serum C-reactive protein detected by means of a near-patient test for human C-reactive protein

The Journal of Small Animal Practice
M Kjelgaard-HansenAsger Lundorff Jensen

Abstract

The aim of the study was to evaluate the reliability of a rapid human C-reactive protein near-patient slide reversed passive latex agglutination test (Randox) for the semi-quantitative determination of canine serum C-reactive protein. The concentration of C-reactive protein was determined in 244 canine serum samples by an established automated immunoturbidimetric method and in various predilutions by a commercially available reversed passive latex agglutination test for human C-reactive protein. The results were compared to assess if the reversed passive latex agglutination test reflected the results of the established method with special emphasis on the reversed passive latex agglutination test's ability to identify samples characterised as positive or negative by the established method. The reversed passive latex agglutination test reflected the C-reactive protein concentration in canine serum samples at all the tested predilutions (undiluted, 1:4, 1:8 and 1:16). When applying a predilution of 1:8, the positive and negative analytical predictive values for discriminating between positive and negative samples (according to the established quantitative method) were high (0.94 [0.82 to 0.99] and 0.97 [0.93 to 0.99], respectively...Continue Reading

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Sep 13, 2006·Veterinary Clinical Pathology·Asger Lundorff Jensen, Mads Kjelgaard-Hansen

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Citations

Aug 11, 2011·Veterinary Clinical Pathology·Hanna D PlickertBarbara Kohn
Feb 8, 2011·Clinics in Laboratory Medicine·Mads Kjelgaard-Hansen, Stine Jacobsen
May 13, 2015·Veterinary Clinical Pathology·Anne-Katherine JasenskyBarbara Kohn
Jul 14, 2010·Journal of Veterinary Diagnostic Investigation : Official Publication of the American Association of Veterinary Laboratory Diagnosticians, Inc·Stefanie KlennerAndreas Moritz
Mar 3, 2019·Dentistry Journal·Mainul HaqueSeraj Zohurul Haque

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